EFFECT OF OLEA OINTMENT AND ACETATE MAFENIDE ON BURN WOUNDS – A RANDOMIZED CLINICAL TRIAL

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ZAHMATKESH MOHSEN; JALILI MANESH MOHAMMAD; BABASHAHABI RONAK

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Journal Paper

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Journal: Iranian Journal of Nursing and Midwifery Research Year:2015 | Volume:20 | Issue:5 Page(s): 599-603

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Title

EFFECT OF OLEA OINTMENT AND ACETATE MAFENIDE ON BURN WOUNDS – A RANDOMIZED CLINICAL TRIAL

Author(s)

ZAHMATKESH MOHSEN | JALILI MANESH MOHAMMAD | BABASHAHABI RONAK | Issue Writer Certificate

Keywords

BURNS

RE-EPITHELIALIZATION

WOUNDS AND INJURIES

WOUND HEALING

Abstract

Background: The main goals in treating BURNS are to accelerate tissue renovation and prevent infection. Topical antibiotics are used in the treatment of BURNS, but they can cause side effects. Recently, a traditional ointment (Olea) has been used in Iran in the treatment of BURNS. This study examines the effect of topical honey ointment in healing of burn patients.Materials and Methods: In this randomized controlled trial (RCT), 30 hospitalized patients selected by conventional sampling (10 in Olea group and 20 in Acetate Mafenide ointment group) were evaluated. Inclusion criteria were: having second‑degree BURNS and body surface area equal to or<40%. One group was treated using topical Olea ointment and the other with Acetate Mafenide ointment (8.5%). Chi‑square, Fisher exact test, and Kaplan–Meier were used. Significance level was considered as P<0.05.Results: None of the patients in the Olea group needed surgery for debridement, while in the second group, 13 patients (65%) needed debridement (P=0.001). In the Olea group, 1 patient (10%) and in the second group, 19 patients (95%) had positive cultures after 7 days (P<0.001). The mean time of granulation tissue formation in the Olea group was 12 days (10.3–13.6) and in the other group, it was 17 days (13.3–20.6) (P<0.001).Conclusions: Olea ointment is a useful treatment for BURNS, and it can prevent infections, accelerate tissue repair, and facilitate debridement. Therefore, using this ointment is recommended for the treatment of BURNS.

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APA: Copy

ZAHMATKESH, MOHSEN, JALILI MANESH, MOHAMMAD, & BABASHAHABI, RONAK. (2015). EFFECT OF OLEA OINTMENT AND ACETATE MAFENIDE ON BURN WOUNDS – A RANDOMIZED CLINICAL TRIAL. IRANIAN JOURNAL OF NURSING AND MIDWIFERY RESEARCH (IJNMR), 20(5), 599-603. SID. https://sid.ir/paper/310812/en

Vancouver: Copy

ZAHMATKESH MOHSEN, JALILI MANESH MOHAMMAD, BABASHAHABI RONAK. EFFECT OF OLEA OINTMENT AND ACETATE MAFENIDE ON BURN WOUNDS – A RANDOMIZED CLINICAL TRIAL. IRANIAN JOURNAL OF NURSING AND MIDWIFERY RESEARCH (IJNMR)[Internet]. 2015;20(5):599-603. Available from: https://sid.ir/paper/310812/en

IEEE: Copy

MOHSEN ZAHMATKESH, MOHAMMAD JALILI MANESH, and RONAK BABASHAHABI, “EFFECT OF OLEA OINTMENT AND ACETATE MAFENIDE ON BURN WOUNDS – A RANDOMIZED CLINICAL TRIAL,” IRANIAN JOURNAL OF NURSING AND MIDWIFERY RESEARCH (IJNMR), vol. 20, no. 5, pp. 599–603, 2015, [Online]. Available: https://sid.ir/paper/310812/en

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