LIMBAL STEM CELLS IN REVIEW

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EBRAHIMI MARZIEH; TAGHIABADI E.; BAHARVAND HOSSEIN

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Journal Paper

Paper Information

Journal: Journal of Ophthalmic and Vision Research Year:2009 | Volume:4 | Issue:1 Page(s): 40-58

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Information Journal Paper

Title

LIMBAL STEM CELLS IN REVIEW

Author(s)

EBRAHIMI MARZIEH | TAGHIABADI E. | BAHARVAND HOSSEIN | Issue Writer Certificate

Keywords

STEM CELLS

LIMBUS CORNEAE

EPITHELIUM

CORNEAL

Abstract

The ocular surface consists of two distinct types of epithelial cells; conjunctival and CORNEAL. Although anatomically continuous, these epithelia comprise two distinct cell populations. CORNEAL STEM CELLS are located at the limbus. The microenvironment of the limbus is important in maintaining “stemness” of the STEM CELLS and also acts as a barrier to conjunctival epithelial cells preventing them from migration onto the CORNEAL surface. Damage to the limbus results in varying degrees of limbal stem cell deficiency with characteristic clinical features including conjunctivalization of the cornea. Regenerative management of CORNEAL conjunctivalization utilizing STEM CELLS comprises of two approaches; limbal auto- or allografts by using existing STEM CELLS and induction and regeneration of ocular tissues from embryonic STEM CELLS. Herein, we review STEM CELLS and limbal STEM CELLS in particular, types of epithelial cells in the cornea, markers of CORNEAL epithelial cells in different stages, as well as the current approach to CORNEAL epithelial regeneration.

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APA: Copy

EBRAHIMI, MARZIEH, TAGHIABADI, E., & BAHARVAND, HOSSEIN. (2009). LIMBAL STEM CELLS IN REVIEW. JOURNAL OF OPHTHALMIC AND VISION RESEARCH, 4(1), 40-58. SID. https://sid.ir/paper/311285/en

Vancouver: Copy

EBRAHIMI MARZIEH, TAGHIABADI E., BAHARVAND HOSSEIN. LIMBAL STEM CELLS IN REVIEW. JOURNAL OF OPHTHALMIC AND VISION RESEARCH[Internet]. 2009;4(1):40-58. Available from: https://sid.ir/paper/311285/en

IEEE: Copy

MARZIEH EBRAHIMI, E. TAGHIABADI, and HOSSEIN BAHARVAND, “LIMBAL STEM CELLS IN REVIEW,” JOURNAL OF OPHTHALMIC AND VISION RESEARCH, vol. 4, no. 1, pp. 40–58, 2009, [Online]. Available: https://sid.ir/paper/311285/en

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