Combined Administration of Melissa officinalis and Boswellia serrata Extracts in an Animal Model of Memory

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MAHBOUBI MOHADDESE; TAGHIZADEH MOHSEN; TALAEI SAYYED ALIREZA; Takht Firozeh Sayyed Mehdi; RASHIDI ALI AKBAR; TAMTAJI OMID REZA

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Journal: Iranian Journal of Psychiatry and Behavioral Sciences Year:2016 | Volume:10 | Issue:3 Page(s): 1-6

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Title

Combined Administration of Melissa officinalis and Boswellia serrata Extracts in an Animal Model of Memory

Author(s)

Keywords

Boswellia serrata

Melissa officinalis

Rat

Scopolamine

Spatial Memory

Abstract

Background: Rata/fa?page=1&sort=1&ftyp=all&fgrp=all&fyrs=all" target="_blank">Boswellia serRata and Melissa officinalis is traditionally used for its memory enhancing effects. Objectives: In this study, we evaluated the protective effects of combined form of these extracts onmemory improvement of Scopolamine treated Rats by the Morris water maze method. MaterialsandMethods: Twogroups (group 1and2) of animals were pretreated withcombinedextracts of B. serRataandM. officinalis (200, 400 mg/Kg body weight) for four weeks and then, 30 minutes before starting the experiment Scopolamine was injected (0. 1 mg/kg body weight) intraperitoneally to pretreated animals. The control group was the animals that were injected by Scopolamine and pre treated with distilled water (group 3). The normal group was treated with distilled water alone (group 4). Results: For time spent and distance, there was no substantial difference between groups 1, 2 and 4, while they had statistical difference with group 3 (P = 0. 001). The Spatial Memory evaluation showed no significant difference between treated groups and normal group. Conclusions: Therefore, the combination of the two extracts had the ability to improve memory as its traditional use.

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APA: Copy

MAHBOUBI, MOHADDESE, TAGHIZADEH, MOHSEN, TALAEI, SAYYED ALIREZA, Takht Firozeh, Sayyed Mehdi, RASHIDI, ALI AKBAR, & TAMTAJI, OMID REZA. (2016). Combined Administration of Melissa officinalis and Boswellia serrata Extracts in an Animal Model of Memory. IRANIAN JOURNAL OF PSYCHIATRY AND BEHAVIORAL SCIENCES (IJPBS), 10(3), 1-6. SID. https://sid.ir/paper/312380/en

Vancouver: Copy

MAHBOUBI MOHADDESE, TAGHIZADEH MOHSEN, TALAEI SAYYED ALIREZA, Takht Firozeh Sayyed Mehdi, RASHIDI ALI AKBAR, TAMTAJI OMID REZA. Combined Administration of Melissa officinalis and Boswellia serrata Extracts in an Animal Model of Memory. IRANIAN JOURNAL OF PSYCHIATRY AND BEHAVIORAL SCIENCES (IJPBS)[Internet]. 2016;10(3):1-6. Available from: https://sid.ir/paper/312380/en

IEEE: Copy

MOHADDESE MAHBOUBI, MOHSEN TAGHIZADEH, SAYYED ALIREZA TALAEI, Sayyed Mehdi Takht Firozeh, ALI AKBAR RASHIDI, and OMID REZA TAMTAJI, “Combined Administration of Melissa officinalis and Boswellia serrata Extracts in an Animal Model of Memory,” IRANIAN JOURNAL OF PSYCHIATRY AND BEHAVIORAL SCIENCES (IJPBS), vol. 10, no. 3, pp. 1–6, 2016, [Online]. Available: https://sid.ir/paper/312380/en

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