THE ROLE OF MICRORNAS IN HUMAN DISEASES

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ARDAKANI A.M.; MOSLEMI NAEINI M.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

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Journal: Avicenna Journal of Medical Biotechnology Year:2010 | Volume:2 | Issue:4 Page(s): 161-179

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Information Journal Paper

Title

THE ROLE OF MICRORNAS IN HUMAN DISEASES

Author(s)

ARDAKANI A.M. | MOSLEMI NAEINI M. | Issue Writer Certificate

Keywords

DISEASE

HUMAN GENOME

MICRORNAS

MIRNA

Abstract

MicroRNAs (miRNAs) are short RNA molecules which bind to target mRNAs, resulting in translational repression and gene silencing and are found in all eukaryotic cells. Approximately 2200 MIRNA genes have been reported to exist in the mammalian genome, from which over 1000 belong to the HUMAN GENOME. Many major cellular functions such as development, differentiation, growth, and metabolism are known to be regulated by MIRNAs. Proximity to other genes in the genome and their locations in introns of coding genes, noncoding genes and exons have been reported to have a major influence on the level of gene expressions in eukaryotic cells. MIRNAs are well conserved in eukaryotic system and are believed to be an essential and evolutionary ancient component of gene regulatory networks. Therefore, in recent years MIRNAs have been studied as a likely candidate for involvement in most biologic processes and have been implicated in many human DISEASEs.

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APA: Copy

ARDAKANI, A.M., & MOSLEMI NAEINI, M.. (2010). THE ROLE OF MICRORNAS IN HUMAN DISEASES. AVICENNA JOURNAL OF MEDICAL BIOTECHNOLOGY (AJMB), 2(4), 161-179. SID. https://sid.ir/paper/313744/en

Vancouver: Copy

ARDAKANI A.M., MOSLEMI NAEINI M.. THE ROLE OF MICRORNAS IN HUMAN DISEASES. AVICENNA JOURNAL OF MEDICAL BIOTECHNOLOGY (AJMB)[Internet]. 2010;2(4):161-179. Available from: https://sid.ir/paper/313744/en

IEEE: Copy

A.M. ARDAKANI, and M. MOSLEMI NAEINI, “THE ROLE OF MICRORNAS IN HUMAN DISEASES,” AVICENNA JOURNAL OF MEDICAL BIOTECHNOLOGY (AJMB), vol. 2, no. 4, pp. 161–179, 2010, [Online]. Available: https://sid.ir/paper/313744/en

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