FOURIER TRANSFORM INFRARED SPECTROSCOPY: A POTENTIAL TECHNIQUE FOR NONINVASIVE DETECTION OF SPERMATOGENESIS

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GILANY KAMBIZ; MOAZENI POURACIL ROUDABEH SADAT; SADEGHI MOHAMMAD REZA

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Journal Paper

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Journal: Avicenna Journal of Medical Biotechnology Year:2014 | Volume:6 | Issue:1 Page(s): 47-52

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Information Journal Paper

Title

FOURIER TRANSFORM INFRARED SPECTROSCOPY: A POTENTIAL TECHNIQUE FOR NONINVASIVE DETECTION OF SPERMATOGENESIS

Author(s)

GILANY KAMBIZ | MOAZENI POURACIL ROUDABEH SADAT | SADEGHI MOHAMMAD REZA | Issue Writer Certificate

Keywords

AZOOSPERMIA

FOURIER TRANSFORM INFRARED SPECTROSCOPY

SEMINAL PLASMA

METABOLOME

Abstract

Background: The SEMINAL PLASMA is an excellent source for noninvasive detection of spermatogenesis. The SEMINAL PLASMA of normospermic and azoospermic men has been analyzed for detection of spermatogenesis.Methods: Optical spectroscopy (Attenuated Total Reflectance-Infrared spectroscopy (ATR-IR) and FOURIER TRANSFORM INFRARED SPECTROSCOPY (FT-IR) has been used to analyze the SEMINAL PLASMA and the METABOLOME of SEMINAL PLASMA for detection of spermatogenesis.Results: The SEMINAL PLASMA of normospermic and azoospermic men has been analyzed by ATR-IR. The results show that there is a pattern variation in the azoospermic men compared to normospermic men. However, the SEMINAL PLASMA is too complex to show significant pattern variation. Therefore, the METABOLOME which is a subcomponent of the SEMINAL PLASMA was analyzed. The SEMINAL PLASMA METABOLOME of normospermic and azoospermic men has been analyzed by FT-IR. A significant pattern change was observed. The data combined with chemometrics analysis showed that significant changes are observed at METABOLOME level.Conclusion: We suggest that FT-IR has the potential as a diagnostic tool instead of testicular biopsy.

Cites

METABOLOMICS: A BIRD’ S EYE VIEW OF INFERTILE MEN: REVIEW ARTICLE

References

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APA: Copy

GILANY, KAMBIZ, MOAZENI POURACIL, ROUDABEH SADAT, & SADEGHI, MOHAMMAD REZA. (2014). FOURIER TRANSFORM INFRARED SPECTROSCOPY: A POTENTIAL TECHNIQUE FOR NONINVASIVE DETECTION OF SPERMATOGENESIS. AVICENNA JOURNAL OF MEDICAL BIOTECHNOLOGY (AJMB), 6(1), 47-52. SID. https://sid.ir/paper/313824/en

Vancouver: Copy

GILANY KAMBIZ, MOAZENI POURACIL ROUDABEH SADAT, SADEGHI MOHAMMAD REZA. FOURIER TRANSFORM INFRARED SPECTROSCOPY: A POTENTIAL TECHNIQUE FOR NONINVASIVE DETECTION OF SPERMATOGENESIS. AVICENNA JOURNAL OF MEDICAL BIOTECHNOLOGY (AJMB)[Internet]. 2014;6(1):47-52. Available from: https://sid.ir/paper/313824/en

IEEE: Copy

KAMBIZ GILANY, ROUDABEH SADAT MOAZENI POURACIL, and MOHAMMAD REZA SADEGHI, “FOURIER TRANSFORM INFRARED SPECTROSCOPY: A POTENTIAL TECHNIQUE FOR NONINVASIVE DETECTION OF SPERMATOGENESIS,” AVICENNA JOURNAL OF MEDICAL BIOTECHNOLOGY (AJMB), vol. 6, no. 1, pp. 47–52, 2014, [Online]. Available: https://sid.ir/paper/313824/en

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