مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Information Journal Paper

Title

DISTRIBUTION AND DIVERSITY OF HMW1A AMONG INVASIVE NONTYPEABLE HAEMOPHILUS INFLUENZAE ISOLATES IN IRAN

Pages

  99-102

Abstract

 Background: The pathogenesis of nontypeable HAEMOPHILUS INFLUENZAe (NTHi) begins with adhesion to the rhinopharyngeal mucosa. Almost 38-80% of NTHi clinical isolates produce proteins that belong to the High Molecular Weight (HMW) family of ADHESINS, which are believed to facilitate colonization.Methods: In the present study, the prevalence of hmwA, which encodes the HMW ad-hesin, was determined for a collection of 32 NTHi isolates. Restriction Fragment Length Polymorphism (RFLP) was performed to advance our understanding of hmwA binding sequence diversity.Results: The results demonstrated that hmwA was detected in 61% of NTHi isolates. According to RFLP, isolates were divided into three groups.Conclusion: Based on these observations, it is hypothesized that some strains of non-typeable HAEMOPHILUS INFLUENZAe infect some specific areas more than other parts.

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    APA: Copy

    SHAHINI SHAMS ABADI, MILAD, SIADAT, SEYED DAVAR, VAZIRI, FARZAM, DAVARI, MEHDI, FATEH, ABOLFAZL, POURAZAR, SHAHIN, ABDOLRAHIMI, FARID, & GHAZANFARI, MORTEZA. (2016). DISTRIBUTION AND DIVERSITY OF HMW1A AMONG INVASIVE NONTYPEABLE HAEMOPHILUS INFLUENZAE ISOLATES IN IRAN. AVICENNA JOURNAL OF MEDICAL BIOTECHNOLOGY (AJMB), 8(2), 99-102. SID. https://sid.ir/paper/313903/en

    Vancouver: Copy

    SHAHINI SHAMS ABADI MILAD, SIADAT SEYED DAVAR, VAZIRI FARZAM, DAVARI MEHDI, FATEH ABOLFAZL, POURAZAR SHAHIN, ABDOLRAHIMI FARID, GHAZANFARI MORTEZA. DISTRIBUTION AND DIVERSITY OF HMW1A AMONG INVASIVE NONTYPEABLE HAEMOPHILUS INFLUENZAE ISOLATES IN IRAN. AVICENNA JOURNAL OF MEDICAL BIOTECHNOLOGY (AJMB)[Internet]. 2016;8(2):99-102. Available from: https://sid.ir/paper/313903/en

    IEEE: Copy

    MILAD SHAHINI SHAMS ABADI, SEYED DAVAR SIADAT, FARZAM VAZIRI, MEHDI DAVARI, ABOLFAZL FATEH, SHAHIN POURAZAR, FARID ABDOLRAHIMI, and MORTEZA GHAZANFARI, “DISTRIBUTION AND DIVERSITY OF HMW1A AMONG INVASIVE NONTYPEABLE HAEMOPHILUS INFLUENZAE ISOLATES IN IRAN,” AVICENNA JOURNAL OF MEDICAL BIOTECHNOLOGY (AJMB), vol. 8, no. 2, pp. 99–102, 2016, [Online]. Available: https://sid.ir/paper/313903/en

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