ASSOCIATION OF SEROTONIN TRANSPORTER GENE POLYMORPHISM WITH RECURRENT APHTHOUS STOMATITIS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

NAJAFI SHAMSOLMOLOUK; MOHAMMADZADEH MAHSA; ZAHEDI AMIRABBAS; HEIDARI MANSOUR; REZAEI NIMA

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Avicenna Journal of Medical Biotechnology Year:2018 | Volume:10 | Issue:1 Page(s): 56-60

Download Full-Text

View:

274

Download:

370

Cites:

Information Journal Paper

Title

ASSOCIATION OF SEROTONIN TRANSPORTER GENE POLYMORPHISM WITH RECURRENT APHTHOUS STOMATITIS

Author(s)

Keywords

5-HTTLPR

PCR

RECURRENT APHTHOUS STOMATITIS (RAS)

SINGLE NUCLEOTIDE POLYMORPHISM

Abstract

Background: Recurrent Aphthous Stomatitis (RAS) is one of the most common diseases of the oral cavity all over the world (5-66%). RAS has a multifactorial etiology, while psychological factors such as stress and anger play a role in its manifestation. The serotonergic mechanisms particularly the serotonin-transporter gene (5-HTT) may affect the risk of psychological alterations and stress response. The aim of the present study was to evaluate the polymorphism of the promoter region of5-HTT (5-HTTLPR) in the patients with RAS, compared to that in the control subjects.Methods: In this case-control study, 100 patients with RAS and 100 healthy subjects were enrolled. PCR was performed on DNA of the samples, using a pair of primers capable of distinguishing S/L alleles and replicating5-HTTLPR.Results: No statistically significant difference existed between LL and LS genotype frequencies in the case and control groups. However, SS genotype frequency was significantly higher in the case group, as compared to the control group (p=0.001).Conclusion: The conclusion of the present study demonstrated that S allele could approximately double the risk of RAS.

Cites

No record.

References

No record.

Cite

APA: Copy

NAJAFI, SHAMSOLMOLOUK, MOHAMMADZADEH, MAHSA, ZAHEDI, AMIRABBAS, HEIDARI, MANSOUR, & REZAEI, NIMA. (2018). ASSOCIATION OF SEROTONIN TRANSPORTER GENE POLYMORPHISM WITH RECURRENT APHTHOUS STOMATITIS. AVICENNA JOURNAL OF MEDICAL BIOTECHNOLOGY (AJMB), 10(1), 56-60. SID. https://sid.ir/paper/313940/en

Vancouver: Copy

NAJAFI SHAMSOLMOLOUK, MOHAMMADZADEH MAHSA, ZAHEDI AMIRABBAS, HEIDARI MANSOUR, REZAEI NIMA. ASSOCIATION OF SEROTONIN TRANSPORTER GENE POLYMORPHISM WITH RECURRENT APHTHOUS STOMATITIS. AVICENNA JOURNAL OF MEDICAL BIOTECHNOLOGY (AJMB)[Internet]. 2018;10(1):56-60. Available from: https://sid.ir/paper/313940/en

IEEE: Copy

SHAMSOLMOLOUK NAJAFI, MAHSA MOHAMMADZADEH, AMIRABBAS ZAHEDI, MANSOUR HEIDARI, and NIMA REZAEI, “ASSOCIATION OF SEROTONIN TRANSPORTER GENE POLYMORPHISM WITH RECURRENT APHTHOUS STOMATITIS,” AVICENNA JOURNAL OF MEDICAL BIOTECHNOLOGY (AJMB), vol. 10, no. 1, pp. 56–60, 2018, [Online]. Available: https://sid.ir/paper/313940/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops