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Information Journal Paper

Title

Bacteriostatic Potency of Fe2O3 Against Enterococcus faecalis in Synergy with Antibiotics by DDST Method

Pages

  176-179

Abstract

 Background: In this study, bacteriostatic potency of the Iron oxide nanoparticles against Enterococcus faecalis (E. faecalis) (a clinical sample and the ATCC11700 strain) was investigated. Methods: Nanoparticles’ bacteriostatic concentration was determined and used to appraise the characteristics of the Iron Oxide (Fe2O3) against the isolates. Antimicro-bial examinations with 108cfu. ml-1 were performed at the baseline. Due to evaluation level of potency, after performing Minimum Inhibitory Concentration (MIC), the as-sessment of death kinetic and susceptibility constant of nanoparticles was done by suspension at two MICs in 0 to 360 min treatment time. Results: Fe2O3 nanoparticles in size range of 10-50 nm demonstrated the most effec-tive susceptibility reaction against E. faecalis and ATCC11700 strain in Z=78. 125 ml/μ g-1 and 39. 0625 ml/μ g-1, respectively. The kinetic reaction of E. faecalis against Fe2O3 sus-pension was supposed to be decreased through the elapse of treatment time, whereas increased concentration was along with bacteria growth after a certain time. So, the efficient concentration of nanoparticles was applied with semi-sensitive and antibiotic resistant for both strains. However, synergism of Fe2O3 nanoparticles with Ceftazidime and Clindamycin revealed a higher susceptibility compared with Fe2O3nanoparticles alone against E. faecalis. Conclusion: The experimental results reveal that Fe2O3 has a strong antimicrobial ef-fect at a certain concentration over the time so could potentially be used for bacterial inhibition and this feature will be strengthened in combination with antibiotics.

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    Cite

    APA: Copy

    Shahbazi, Erfan, Morshedzadeh, Firouzeh, & Zaeifi, Davood. (2019). Bacteriostatic Potency of Fe2O3 Against Enterococcus faecalis in Synergy with Antibiotics by DDST Method. AVICENNA JOURNAL OF MEDICAL BIOTECHNOLOGY (AJMB), 11(2), 176-179. SID. https://sid.ir/paper/314022/en

    Vancouver: Copy

    Shahbazi Erfan, Morshedzadeh Firouzeh, Zaeifi Davood. Bacteriostatic Potency of Fe2O3 Against Enterococcus faecalis in Synergy with Antibiotics by DDST Method. AVICENNA JOURNAL OF MEDICAL BIOTECHNOLOGY (AJMB)[Internet]. 2019;11(2):176-179. Available from: https://sid.ir/paper/314022/en

    IEEE: Copy

    Erfan Shahbazi, Firouzeh Morshedzadeh, and Davood Zaeifi, “Bacteriostatic Potency of Fe2O3 Against Enterococcus faecalis in Synergy with Antibiotics by DDST Method,” AVICENNA JOURNAL OF MEDICAL BIOTECHNOLOGY (AJMB), vol. 11, no. 2, pp. 176–179, 2019, [Online]. Available: https://sid.ir/paper/314022/en

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