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Information Journal Paper

Title

Editorial: The Protein Subcellular Mislocalization in Human Cancers

Pages

  0-0

Keywords

Not Registered.

Abstract

 Several sets of proteins exist in eukaryotic cells wherein accurately localized in appropriate cellular locations containing plasma membrane, cytoplasm, nucleus and different membrane-enclosed organelles. Each protein is involved in distinct biochemical processes within the normal cell; therefore, the correct subcellular localization of protein is vital; as it provides the physiological context for protein function. However, protein mislocalization described as changing the appropriate subcellular localization of protein, was reported as a key feature of many proteins in a variety of human cancers 1. Mislo-calization has important implications in alteration of activation condition, biological function and interaction network of a protein. Particularly, the aberrant localization of tumor-suppressor proteins and proto-oncoproteins can alter their func-tions, respectively in either suppressing or supporting the cancer initiation in normal cells whereby cancer development, metastasis and drug resistance are increased....

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    Cite

    APA: Copy

    GHAEMIMANESH, FATEMEH. (2020). Editorial: The Protein Subcellular Mislocalization in Human Cancers. AVICENNA JOURNAL OF MEDICAL BIOTECHNOLOGY (AJMB), 12(1), 0-0. SID. https://sid.ir/paper/314055/en

    Vancouver: Copy

    GHAEMIMANESH FATEMEH. Editorial: The Protein Subcellular Mislocalization in Human Cancers. AVICENNA JOURNAL OF MEDICAL BIOTECHNOLOGY (AJMB)[Internet]. 2020;12(1):0-0. Available from: https://sid.ir/paper/314055/en

    IEEE: Copy

    FATEMEH GHAEMIMANESH, “Editorial: The Protein Subcellular Mislocalization in Human Cancers,” AVICENNA JOURNAL OF MEDICAL BIOTECHNOLOGY (AJMB), vol. 12, no. 1, pp. 0–0, 2020, [Online]. Available: https://sid.ir/paper/314055/en

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