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Information Journal Paper

Title

SERUM CORTISOL LEVELS AS A PREDICTOR OF NEUROLOGIC SURVIVAL IN SUCCESSFULLY RESUSCITATED VICTIMS OF CARDIOPULMONARY ARREST

Pages

  107-111

Abstract

 Introduction: Out-of-hospital cardiac arrest (OHCA) is the most stressful lifetime event for the victims and an important issue for the emergency physicians. The status of the hypothalamic pituitary- adrenal axis (HPA) function in successfully resuscitated victims of CARDIOPULMONARY ARREST has been recently of an interest for the researchers.Methods: In a prospective cohort study, 50 successfully resuscitated OHCA victims’ serum CORTISOL LEVELs were measured 5 minutes and 1 hour after return of spontaneous circulation (ROSC). The data were analyzed comparing the one-week neurologic survival.Results: Fifty blood samples were obtained for serum CORTISOL LEVELs after 5 minutes of ROSC. Fourteen patients (28%) pronounced death during one hour after CPR. Blood sample from living 36 patients after one hour post-CPR were obtained for second cortisol assay. Eleven patients (22%) were neurologically survived after one week. Seven patients (14%) were discharged finally from hospital with good neurologic recovery. The serum CORTISOL LEVELs in both the neurologically surviving and the nonsurviving after 5 minutes of ROSC patients were 63.4±13.6 and 43.2±25.5 (microg/ml), (mean±S.D., respectively) and after 1 hour of ROSC patients’ serum CORTISOL LEVELs were 64.9±13.1 and 47.3±27.1 (microg/ml), (mean±S.D., respectively). The difference was significantly higher in neurologically survived group inboth 5 minutes and 1 hour after ROSC (P=0.015 and 0.013 respectively).Conclusion: serum CORTISOL LEVELs after 5 minutes and one hour of ROSC in victims of CARDIOPULMONARY ARRESTare significantly higher in neurologically survived than non-survived patients.

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    APA: Copy

    TAVAKOLI, NADER, BIDARI, ALI, & SHAMS VAHDATI, SAMAD. (2012). SERUM CORTISOL LEVELS AS A PREDICTOR OF NEUROLOGIC SURVIVAL IN SUCCESSFULLY RESUSCITATED VICTIMS OF CARDIOPULMONARY ARREST. JOURNAL OF CARDIOVASCULAR AND THORACIC RESEARCH, 4(4), 107-111. SID. https://sid.ir/paper/314904/en

    Vancouver: Copy

    TAVAKOLI NADER, BIDARI ALI, SHAMS VAHDATI SAMAD. SERUM CORTISOL LEVELS AS A PREDICTOR OF NEUROLOGIC SURVIVAL IN SUCCESSFULLY RESUSCITATED VICTIMS OF CARDIOPULMONARY ARREST. JOURNAL OF CARDIOVASCULAR AND THORACIC RESEARCH[Internet]. 2012;4(4):107-111. Available from: https://sid.ir/paper/314904/en

    IEEE: Copy

    NADER TAVAKOLI, ALI BIDARI, and SAMAD SHAMS VAHDATI, “SERUM CORTISOL LEVELS AS A PREDICTOR OF NEUROLOGIC SURVIVAL IN SUCCESSFULLY RESUSCITATED VICTIMS OF CARDIOPULMONARY ARREST,” JOURNAL OF CARDIOVASCULAR AND THORACIC RESEARCH, vol. 4, no. 4, pp. 107–111, 2012, [Online]. Available: https://sid.ir/paper/314904/en

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