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Information Journal Paper

Title

ANTIBACTERIAL EFFECTS OF SCROPHULARIA STRIATA SEED AQUEOUS EXTRACT ON STAPHYLOCOCCUS AUREUS

Pages

  58-63

Abstract

 Plant-based drugs are regarded promising recently. Scrophularia has been shown various biological activities such as antimicrobial, antitumor and anti-inflammatory properties. According to pervious researches, bacteria are becoming resistant to some kinds of antibiotics, so it is prominent to find more reliable sources against them. Here STAPHYLOCOCCUS AUREUS as a common type of Gram- positive bacteria has been chosen for this in vitro study. After culturing this bacterium, it was treated with various dosages of SCROPHULARIA STRIATA seed aqueous extract and tetracycline, and then its antibacterial effect was assessed by spectrophotometery method based on bacteria population alteration after 24h incubation. In order to investigate probable side effects of the seed extract its effect on human fibroblast cells has been studied. MTT assay was applied for cell survival determination of human fibroblast cells after 24h. Findings indicate that bacterial population has been declined between 1 to 20 mg mL-1 dosages of the extract, which 5 mg mL-1 is the most effective dosage without containing any cytotoxic effect on human fibroblast cells. In fact extract not only has no antiproliferation properties but also has evoked cell profileration, so it can be consider as a cell growth factor. Tetracycline, on the contrary, showed its potent impact merely in highest dosages with noticeable side effects. It can be concluded that, SCROPHULARIA STRIATA could be possibly a promising antibiotic which shows significant antibacterial properties, and with lesser side effects.

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    APA: Copy

    ZAMANIAN AZODI, MONA, ARDESHIRYLAJIMI, ABDOLREZA, AHMADI, N., AHMADI, NAYEBALI, REZAEE, MOHAMAD BAGHER, AZIZI JALILIAN, FARID, & KHODARAHMI, REZA. (2013). ANTIBACTERIAL EFFECTS OF SCROPHULARIA STRIATA SEED AQUEOUS EXTRACT ON STAPHYLOCOCCUS AUREUS. ARCHIVES OF ADVANCES IN BIOSCIENCES (JOURNAL OF PARAMEDICAL SCIENCES), 4(1), 58-63. SID. https://sid.ir/paper/315881/en

    Vancouver: Copy

    ZAMANIAN AZODI MONA, ARDESHIRYLAJIMI ABDOLREZA, AHMADI N., AHMADI NAYEBALI, REZAEE MOHAMAD BAGHER, AZIZI JALILIAN FARID, KHODARAHMI REZA. ANTIBACTERIAL EFFECTS OF SCROPHULARIA STRIATA SEED AQUEOUS EXTRACT ON STAPHYLOCOCCUS AUREUS. ARCHIVES OF ADVANCES IN BIOSCIENCES (JOURNAL OF PARAMEDICAL SCIENCES)[Internet]. 2013;4(1):58-63. Available from: https://sid.ir/paper/315881/en

    IEEE: Copy

    MONA ZAMANIAN AZODI, ABDOLREZA ARDESHIRYLAJIMI, N. AHMADI, NAYEBALI AHMADI, MOHAMAD BAGHER REZAEE, FARID AZIZI JALILIAN, and REZA KHODARAHMI, “ANTIBACTERIAL EFFECTS OF SCROPHULARIA STRIATA SEED AQUEOUS EXTRACT ON STAPHYLOCOCCUS AUREUS,” ARCHIVES OF ADVANCES IN BIOSCIENCES (JOURNAL OF PARAMEDICAL SCIENCES), vol. 4, no. 1, pp. 58–63, 2013, [Online]. Available: https://sid.ir/paper/315881/en

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