ANTIMICROBIAL RESISTANCE PATTERNS AND PREVALENCE OF BLAPER-1 AND BLAVEB-1 GENES AMONG ESBL-PRODUCING PSEUDOMONAS AERUGINOSA ISOLATES IN WEST OF IRAN

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

ALIKHANI MOHAMMAD YOUSEF; KARIMI TABAR ZAHRA; MIHANI FATEMEH; KALANTAR ENAYAT; KARAMI PEGMAN; SADEGHI MAHNAZ; AHDI KHOSROSHAHI SHIVA; FARAJNIA SAFAR

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Jundishapur Journal of Microbiology Year:2014 | Volume:7 | Issue:1 Page(s): 0-0

Download Full-Text

View:

508

Download:

175

Cites:

Information Journal Paper

Title

ANTIMICROBIAL RESISTANCE PATTERNS AND PREVALENCE OF BLAPER-1 AND BLAVEB-1 GENES AMONG ESBL-PRODUCING PSEUDOMONAS AERUGINOSA ISOLATES IN WEST OF IRAN

Author(s)

Keywords

PSEUDOMONAS AERUGINOSA

ANTIMICROBIAL DRUG RESISTANCE

BETA-LACTAMASE

Abstract

Background: PSEUDOMONAS AERUGINOSA is a leading cause of nosocomial infections worldwide. Resistance of P. aeruginosa strains to the broad-spectrum cephalosporins may be caused by extended-spectrum b-lactamases (ESBLs).Objectives: The aim of this study was to determine the antimicrobial resistance patterns and prevalence of PER-1 and VEB-1 type genes among ESBL producing strains of P. aeruginosa.Material and Methods: A total of 106 P. aeruginosa isolates were collected from two university hospitals in Hamadan, Iran, during a7-month study (2009). The antimicrobial susceptibility of isolates was determined by disc diffusion method and interpreted according to the clinical and laboratory standards institute (CLSI) recommendations. Production of ESBL was determined by combined disk test and presence of PER-1 and VEB-1 type ESBL genes was identified by PCR.Results: The resistance against broad-spectrum cephalosporins and monobactames were: cefepime (97%), cefotaxime (92.5%) ceftazidime (51%), and aztreonam (27%). Ciprofloxacin (91.5%), imipenem (84.9%) and meropenem (82.1%) were the most effective anti-pseudomonas agents in this study. The results revealed that 88.7% of the isolates were multidrug resistant, 58.25% of those were ESBL positive. Sixteen (26.6%), 9 (15%) and 3 (5%) strains among ESBL-producing strains contained blaPER-1, blaVEB and blaPER-1-blaVEB, respectively.Conclusions: This study highlighted the need to establish antimicrobial resistance surveillance networks for P. aeruginosa to determine the appropriate empirical treatment regimens. The high prevalence of multidrug resistance and production of ESBLs in P. aeruginosa isolates confirms the necessity of protocols considering these issues in the hospitals.

Cites

MORPHOLOGICAL AND BACTERICIDAL EFFECTS OF AMIKACIN, MEROPENEM AND IMIPENEM ON PSEUDOMONAS AERUGINOSA

References

No record.

Cite

APA: Copy

ALIKHANI, MOHAMMAD YOUSEF, KARIMI TABAR, ZAHRA, MIHANI, FATEMEH, KALANTAR, ENAYAT, KARAMI, PEGMAN, SADEGHI, MAHNAZ, AHDI KHOSROSHAHI, SHIVA, & FARAJNIA, SAFAR. (2014). ANTIMICROBIAL RESISTANCE PATTERNS AND PREVALENCE OF BLAPER-1 AND BLAVEB-1 GENES AMONG ESBL-PRODUCING PSEUDOMONAS AERUGINOSA ISOLATES IN WEST OF IRAN. JUNDISHAPUR JOURNAL OF MICROBIOLOGY (JJM), 7(1), 0-0. SID. https://sid.ir/paper/317351/en

Vancouver: Copy

ALIKHANI MOHAMMAD YOUSEF, KARIMI TABAR ZAHRA, MIHANI FATEMEH, KALANTAR ENAYAT, KARAMI PEGMAN, SADEGHI MAHNAZ, AHDI KHOSROSHAHI SHIVA, FARAJNIA SAFAR. ANTIMICROBIAL RESISTANCE PATTERNS AND PREVALENCE OF BLAPER-1 AND BLAVEB-1 GENES AMONG ESBL-PRODUCING PSEUDOMONAS AERUGINOSA ISOLATES IN WEST OF IRAN. JUNDISHAPUR JOURNAL OF MICROBIOLOGY (JJM)[Internet]. 2014;7(1):0-0. Available from: https://sid.ir/paper/317351/en

IEEE: Copy

MOHAMMAD YOUSEF ALIKHANI, ZAHRA KARIMI TABAR, FATEMEH MIHANI, ENAYAT KALANTAR, PEGMAN KARAMI, MAHNAZ SADEGHI, SHIVA AHDI KHOSROSHAHI, and SAFAR FARAJNIA, “ANTIMICROBIAL RESISTANCE PATTERNS AND PREVALENCE OF BLAPER-1 AND BLAVEB-1 GENES AMONG ESBL-PRODUCING PSEUDOMONAS AERUGINOSA ISOLATES IN WEST OF IRAN,” JUNDISHAPUR JOURNAL OF MICROBIOLOGY (JJM), vol. 7, no. 1, pp. 0–0, 2014, [Online]. Available: https://sid.ir/paper/317351/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops