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Information Journal Paper

Title

Anti-Candida Activities and GC Mass Analysis of Seeds Hydroalcohlic Extract of Rumex obtusifolius

Pages

  00-00

Abstract

 drugs resistance in some Candida species and their side effects, conducting research to find new resources, especially medicinal plants, are of prime importance. Objectives: The present study aimed at evaluating anti-Candida activities and antioxidant function of hydroalcohlic extract of seeds of Rumex obtusifolius and analyzing GC mass for the determined material, which included especial formulated extract. Methods: The Rumex obtusifolius seeds were extracted using Ethyl acetate: methanol: distilled water (6: 3: 1) by Soxhelet system. The antifungal activity as well as total free phenolics and flavonoids content were examined. The extract was carried out against 40 isolated Candida species such as Candida albicans and C. glabrata through well diffusion method. In addition, hydroalcoholic extraction of R. obtusifolius was evaluated for its antioxidant capacities using 1-diphenyl-2-picrylhydrazyl radical scavenging. The components of the extract were analyzed via Gas chromatography-Mass spectrometry (GC-Mass) instrument. Results: The minimum inhibitory concentration (MIC) values were 100-150  g/ L for C. albicans 150  g/ L for C. glabrata. The hydroalcoholic extract can strongly scavenge DPPH radical, and its antioxidant capacities may be correlated with the total free phenolics and total flavonoids. This study revealed the highest antioxidant capacity in the seeds of R. obtusifolius compared to the control groups. Conclusions: The extract contained a highamountof phenolic compounds, and its antioxidant activity was significant. The seed of R. obtusifolius has strong anticandidial and antioxidant activities, which may be due to the presence of high levels of phenolic compounds, particularly pyrogallol.

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    APA: Copy

    NAZARI, HOSSEIN, Bakhshandeh, Neda, Gholami, Mahbubeh, MEHRZAD, JAMSHID, & BINESHIAN, FARAHNAZ. (2017). Anti-Candida Activities and GC Mass Analysis of Seeds Hydroalcohlic Extract of Rumex obtusifolius. JUNDISHAPUR JOURNAL OF MICROBIOLOGY (JJM), 10(7), 00-00. SID. https://sid.ir/paper/317883/en

    Vancouver: Copy

    NAZARI HOSSEIN, Bakhshandeh Neda, Gholami Mahbubeh, MEHRZAD JAMSHID, BINESHIAN FARAHNAZ. Anti-Candida Activities and GC Mass Analysis of Seeds Hydroalcohlic Extract of Rumex obtusifolius. JUNDISHAPUR JOURNAL OF MICROBIOLOGY (JJM)[Internet]. 2017;10(7):00-00. Available from: https://sid.ir/paper/317883/en

    IEEE: Copy

    HOSSEIN NAZARI, Neda Bakhshandeh, Mahbubeh Gholami, JAMSHID MEHRZAD, and FARAHNAZ BINESHIAN, “Anti-Candida Activities and GC Mass Analysis of Seeds Hydroalcohlic Extract of Rumex obtusifolius,” JUNDISHAPUR JOURNAL OF MICROBIOLOGY (JJM), vol. 10, no. 7, pp. 00–00, 2017, [Online]. Available: https://sid.ir/paper/317883/en

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