Classification of Pathogenic Bacteria in Cerebrospinal Fluid of Patients with Intracranial Infection After Neurosurgery and Selective Use of Antibacterial Agents

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Chen Yunxiang; Li Zhengyang; Liu Jihong; Fan Yuejun; Tong Minfeng; Lu Jianglong; Zhou Gezhi

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Jundishapur Journal of Microbiology Year:2018 | Volume:11 | Issue:4 Page(s): 0-0

Download Full-Text

View:

176

Download:

Cites:

Information Journal Paper

Title

Classification of Pathogenic Bacteria in Cerebrospinal Fluid of Patients with Intracranial Infection After Neurosurgery and Selective Use of Antibacterial Agents

Author(s)

Keywords

Neurosurgery

Intracranial Infection

Cerebrospinal Fluid

Pathogenic Bacteria

Antibacterial Agents

Abstract

Background: Anti-infective treatment has become troublesome owing to aggravated resistance to Antibacterial Agents. Objectives: This study aimed at investigating the distribution characteristics and drug resistance changes of Pathogenic Bacteria in Cerebrospinal Fluid (CSF) of patients with Intracranial Infection receiving Neurosurgery, and to provide evidence for rational use of Antibacterial Agents. Methods: Bacteria were collected from CSF cultures of all patients receiving Neurosurgery in the hospital of the current research, from January 2013 to December 2015, and the same types of strains cultured from each case during the same infection were combined. A hospital information system (HIS) was then used to analyze the data of 120 patients, who received Neurosurgery from January 2015 to June 2016 and had positive CSF bacterial culture results after surgery, and to treat them by rationally selecting Antibacterial Agents. Results: A total of 845 Pathogenic Bacterial strains were isolated from the CSF samples and cultured, of which 629 were Gramnegative bacteria, accounting for 74. 4%. Particularly, Acinetobacter baumannii had severe pan-resistance. There were 216 Grampositive bacteria, which accounted for 25. 6% of all strains, and were mainly methicillin-resistant staphylococci, being basically resistant to penicillins and only susceptible to vancomycin and linezolid. After rational selection of Antibacterial Agents using HIS, based on the retrospective analysis results, 101 of the 120 patients were cured by vancomycin and linezolid (cure rate: 84. 17%). Conclusions: Since the treatment outcomes after rational selection of Antibacterial Agents (i. e. vancomycin and linezolid) using HIS were satisfactory, the findings of retrospective analysis are of high clinical value.

Cites

No record.

References

No record.

Cite

APA: Copy

Chen, Yunxiang, Li, Zhengyang, Liu, Jihong, Fan, Yuejun, Tong, Minfeng, Lu, Jianglong, & Zhou, Gezhi. (2018). Classification of Pathogenic Bacteria in Cerebrospinal Fluid of Patients with Intracranial Infection After Neurosurgery and Selective Use of Antibacterial Agents. JUNDISHAPUR JOURNAL OF MICROBIOLOGY (JJM), 11(4), 0-0. SID. https://sid.ir/paper/317933/en

Vancouver: Copy

Chen Yunxiang, Li Zhengyang, Liu Jihong, Fan Yuejun, Tong Minfeng, Lu Jianglong, Zhou Gezhi. Classification of Pathogenic Bacteria in Cerebrospinal Fluid of Patients with Intracranial Infection After Neurosurgery and Selective Use of Antibacterial Agents. JUNDISHAPUR JOURNAL OF MICROBIOLOGY (JJM)[Internet]. 2018;11(4):0-0. Available from: https://sid.ir/paper/317933/en

IEEE: Copy

Yunxiang Chen, Zhengyang Li, Jihong Liu, Yuejun Fan, Minfeng Tong, Jianglong Lu, and Gezhi Zhou, “Classification of Pathogenic Bacteria in Cerebrospinal Fluid of Patients with Intracranial Infection After Neurosurgery and Selective Use of Antibacterial Agents,” JUNDISHAPUR JOURNAL OF MICROBIOLOGY (JJM), vol. 11, no. 4, pp. 0–0, 2018, [Online]. Available: https://sid.ir/paper/317933/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops