RELATIONSHIP BETWEEN SERUM HOMOCYSTEINE AND OTHER PARAMETERS IN OVERT DIABETIC NEPHROPATHY

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MOGHADASIMOUSAVI SARA SADAT; NOURI MAJALAN NADER

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Journal Paper

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Journal: Iranian Journal of Diabetes and Obesity Year:2012 | Volume:4 | Issue:1 Page(s): 15-18

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Information Journal Paper

Title

RELATIONSHIP BETWEEN SERUM HOMOCYSTEINE AND OTHER PARAMETERS IN OVERT DIABETIC NEPHROPATHY

Author(s)

MOGHADASIMOUSAVI SARA SADAT | NOURI MAJALAN NADER | Issue Writer Certificate

Keywords

HOMOCYSTEINE

DIABETIC NEPHROPATHIES

PROTEINURIA

Abstract

OBJECTIVE: Level of serum HOMOCYSTEINE is remarkably common among patients with moderate to sever renal failure. We assessed whether serum HOMOCYSTEINE concentrations were correlated with PROTEINURIA in overt diabetic nephropathy.MATERIALS AND METHODS: A cross-sectional study was carried out on 45 patients (29 males, 16 females) with overt PROTEINURIA. All subjects had type 2 diabetes. Data included age, sex, hypertension, serum creatinine, creatinine clearance, 24-hour urine PROTEINURIA, lipid profiles and serum HOMOCYSTEINE.RESULTS: The mean of serum HOMOCYSTEINE concentrations was 18±7.7 mmol/L (4.6-42), having 31 (70%) hyperHOMOCYSTEINEmia. The mean of 24-hour urine PROTEINURIA was 1515±996 mg, for serum creatinine 1.9±0.7 mg, and for creatinine clearance, it was 97±26.6 mL/min. Serum HOMOCYSTEINE had a negative correlation with creatinine clearance (r=-0.4, p=0.007) and revealed no correlation with 24-hour PROTEINURIA (p=0.9).CONCLUSION: In overt nephropathy in diabetes type 2, patients with higher HOMOCYSTEINE had lower creatinine clearance. However, there was no correlation between HOMOCYSTEINE and overt PROTEINURIA.

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APA: Copy

MOGHADASIMOUSAVI, SARA SADAT, & NOURI MAJALAN, NADER. (2012). RELATIONSHIP BETWEEN SERUM HOMOCYSTEINE AND OTHER PARAMETERS IN OVERT DIABETIC NEPHROPATHY. IRANIAN JOURNAL OF DIABETES AND OBESITY, 4(1), 15-18. SID. https://sid.ir/paper/318135/en

Vancouver: Copy

MOGHADASIMOUSAVI SARA SADAT, NOURI MAJALAN NADER. RELATIONSHIP BETWEEN SERUM HOMOCYSTEINE AND OTHER PARAMETERS IN OVERT DIABETIC NEPHROPATHY. IRANIAN JOURNAL OF DIABETES AND OBESITY[Internet]. 2012;4(1):15-18. Available from: https://sid.ir/paper/318135/en

IEEE: Copy

SARA SADAT MOGHADASIMOUSAVI, and NADER NOURI MAJALAN, “RELATIONSHIP BETWEEN SERUM HOMOCYSTEINE AND OTHER PARAMETERS IN OVERT DIABETIC NEPHROPATHY,” IRANIAN JOURNAL OF DIABETES AND OBESITY, vol. 4, no. 1, pp. 15–18, 2012, [Online]. Available: https://sid.ir/paper/318135/en

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