Six Weeks Resistance Training Effect on FTO Expression in Type II Diabetes Rats

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Yazdanpazhooh Somayeh; BANAEIFAR ABDOLALI; ARSHADI SAJAD; EIZADI MOJTABA

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Journal Paper

Paper Information

Journal: Iranian Journal of Diabetes and Obesity Year:2018 | Volume:10 | Issue:4 Page(s): 216-222

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Title

Six Weeks Resistance Training Effect on FTO Expression in Type II Diabetes Rats

Author(s)

Yazdanpazhooh Somayeh | BANAEIFAR ABDOLALI | ARSHADI SAJAD | EIZADI MOJTABA | Issue Writer Certificate

Keywords

Diabetes mellitus

Gene expression

Glucose

Resistance training

Abstract

Objective: Fat mass and obesity associated gene (FTO) was identified as a candidate gene contributing to obesity, insulin resistance and type 2 Diabetes mellitus (T2DM). This study aimed to determine the effect of Resistance training on FTO expression in subcutaneous fat tissue, insulin resistance and Glucose in T2DM rats. Materials and Methods: For this purpose, sixteen obese males wistar rats with T2DM were randomly divided into exercise (n= 8) and control (n= 8) groups. Exercise group were completed six weeks Resistance training included climbed on a stepladder (5 days per week) and control group did not participate in exercise intervention. Relative expression of FTO expression in subcutaneous fat tissue, fasting Glucose and insulin resistance were measured 48 hours after last exercise session of two groups. Independent t-test used to compare data. Results: In comparison with control group, Resistance training induced significant decrease in fasting Glucose (P-value: 0. 001) and insulin resistance (P-value: 0. 001). But FTO expression in subcutaneous fat tissue did not change by Resistance training (Pvalue: 0. 318). Conclusion: Resistance training did not influence FTO expression in fat tissue of T2DM rats. Improved insulin resistance and Glucose can be attributed to the change in other genetic or hormonal factors by Resistance training.

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APA: Copy

Yazdanpazhooh, Somayeh, BANAEIFAR, ABDOLALI, ARSHADI, SAJAD, & EIZADI, MOJTABA. (2018). Six Weeks Resistance Training Effect on FTO Expression in Type II Diabetes Rats. IRANIAN JOURNAL OF DIABETES AND OBESITY, 10(4), 216-222. SID. https://sid.ir/paper/318238/en

Vancouver: Copy

Yazdanpazhooh Somayeh, BANAEIFAR ABDOLALI, ARSHADI SAJAD, EIZADI MOJTABA. Six Weeks Resistance Training Effect on FTO Expression in Type II Diabetes Rats. IRANIAN JOURNAL OF DIABETES AND OBESITY[Internet]. 2018;10(4):216-222. Available from: https://sid.ir/paper/318238/en

IEEE: Copy

Somayeh Yazdanpazhooh, ABDOLALI BANAEIFAR, SAJAD ARSHADI, and MOJTABA EIZADI, “Six Weeks Resistance Training Effect on FTO Expression in Type II Diabetes Rats,” IRANIAN JOURNAL OF DIABETES AND OBESITY, vol. 10, no. 4, pp. 216–222, 2018, [Online]. Available: https://sid.ir/paper/318238/en

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