TRAMADOL OVERDOSE AND APNEA IN HOSPITALIZED CHILDREN, A REVIEW OF 20 CASES

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

HASSANIAN MOGHADDAM HOSSEIN; FARNAGHI FARIBA; RAHIMI MITRA

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: RESEARCH IN PHARMACEUTICAL SCIENCES (RPS) Year:2015 | Volume:10 | Issue:6 Page(s): 544-552

Download Full-Text

View:

226

Download:

178

Cites:

Information Journal Paper

Title

TRAMADOL OVERDOSE AND APNEA IN HOSPITALIZED CHILDREN, A REVIEW OF 20 CASES

Author(s)

HASSANIAN MOGHADDAM HOSSEIN | FARNAGHI FARIBA | RAHIMI MITRA | Issue Writer Certificate

Keywords

TRAMADOL

INTOXICATION

OVERDOSE

INTENSIVE CARE UNITS

PEDIATRIC

APNEA

Abstract

We aimed to determine the clinical manifestations of TRAMADOL INTOXICATION in children and to find its potential poor prognostic factors. In a retrospective study, from 1363 cases of admitted PEDIATRIC poisoning, all TRAMADOL-exposed hospitalized patients younger than 12 years were included in the study. They were hospitalized between March 2010 and April 2012 to the only referral hospital for PEDIATRIC poisoned patients in Tehran, Iran. Data including age, weight, gender, ingested dose (determined by history), pupil size, seizure, APNEA, treatment interventions, and laboratory results was collected using chart review of the hospitalized intoxicated children. Twenty children with a mean age of 3.7±2.9 years were identified amongst children during this 26-month period of whom, 14 (70%) had a decreased level of consciousness, 3 (15%) experienced APNEA, and four (20%) had nausea and vomiting. Witnessed seizure did not occur in any of these patients. All patients were referred to hospital within 10.5 h of the exposure. The mean ingested dose was 9.6±5.5 mg/kg. There was no significant relation between APNEA and the estimated toxic dose. APNEA was more common in children who had presented with respiratory acidosis (Relative risk=3.8, 95% CI=1.6, 8.7, P=0.043). All patients survived. Patients with APNEA were managed conservatively by naloxone and recovered without need for intubation. Respiratory depression might occur at doses just above the therapeutic dose. We recommend an observation time of 12 h for all asymptomatic children who have ingested any dose greater than the therapeutic one.

Cites

No record.

References

No record.

Cite

APA: Copy

HASSANIAN MOGHADDAM, HOSSEIN, FARNAGHI, FARIBA, & RAHIMI, MITRA. (2015). TRAMADOL OVERDOSE AND APNEA IN HOSPITALIZED CHILDREN, A REVIEW OF 20 CASES. RESEARCH IN PHARMACEUTICAL SCIENCES (RPS), 10(6), 544-552. SID. https://sid.ir/paper/318418/en

Vancouver: Copy

HASSANIAN MOGHADDAM HOSSEIN, FARNAGHI FARIBA, RAHIMI MITRA. TRAMADOL OVERDOSE AND APNEA IN HOSPITALIZED CHILDREN, A REVIEW OF 20 CASES. RESEARCH IN PHARMACEUTICAL SCIENCES (RPS)[Internet]. 2015;10(6):544-552. Available from: https://sid.ir/paper/318418/en

IEEE: Copy

HOSSEIN HASSANIAN MOGHADDAM, FARIBA FARNAGHI, and MITRA RAHIMI, “TRAMADOL OVERDOSE AND APNEA IN HOSPITALIZED CHILDREN, A REVIEW OF 20 CASES,” RESEARCH IN PHARMACEUTICAL SCIENCES (RPS), vol. 10, no. 6, pp. 544–552, 2015, [Online]. Available: https://sid.ir/paper/318418/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops