ASSOCIATION BETWEEN SERUM FERRITIN LEVEL, CARDIAC AND HEPATIC T2-STAR MRI IN PATIENTS WITH MAJOR Β-THALASSEMIA

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EGHBALI A.; TAHERAHMADI H.; SHAHBAZI M.; BAGHERI B.; EBRAHIMI L.

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Journal Paper

Paper Information

Journal: IRANIAN JOURNAL OF PEDIATRIC HEMATOLOGY AND ONCOLOGY Year:2014 | Volume:4 | Issue:1 Page(s): 17-21

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Title

ASSOCIATION BETWEEN SERUM FERRITIN LEVEL, CARDIAC AND HEPATIC T2-STAR MRI IN PATIENTS WITH MAJOR Β-THALASSEMIA

Author(s)

Keywords

FERRITIN

IRON CHELATOR

MAJOR THALASSEMIA

T2*MRI

Abstract

Background: Frequent blood transfusion is often associated with iron overload. Proper use of IRON CHELATORs to treat iron overload requires an accurate measurement of iron levels. Magnetic resonance T2-star (T2* MRI) can measure iron level in the heart and liver. Our goal was to see whether an association exists between serum FERRITIN level and T2* MRI in patients with major beta thalassemia.Materials and Methods: Sixty patients with a diagnosis of major beta thalassemia were enrolled in the study. They were older than five years old and needed regular transfusion. Cardiac and hepatic T2*MRI and mean serum FERRITIN levels were measured within 3 months.Results: No significant correlation was observed between serum FERRITIN level and cardiac T2*MRI (p=0.361, r=-0.120).However, a significant correlation was observed between serum FERRITIN and liver T2*MRI (p=0.021, r=-0.297).Conclusion: Our results showed an association between hepatic T2*MRI and serum FERRITIN level.

Cites

CARDIAC INVOLVEMENT IN PATIENTS WITH THALASSEMIA MAJOR AND CONTROL GROUP: A CASE-CONTROL STUDY

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APA: Copy

EGHBALI, A., TAHERAHMADI, H., SHAHBAZI, M., BAGHERI, B., & EBRAHIMI, L.. (2014). ASSOCIATION BETWEEN SERUM FERRITIN LEVEL, CARDIAC AND HEPATIC T2-STAR MRI IN PATIENTS WITH MAJOR Β-THALASSEMIA. IRANIAN JOURNAL OF PEDIATRIC HEMATOLOGY AND ONCOLOGY, 4(1), 17-21. SID. https://sid.ir/paper/320618/en

Vancouver: Copy

EGHBALI A., TAHERAHMADI H., SHAHBAZI M., BAGHERI B., EBRAHIMI L.. ASSOCIATION BETWEEN SERUM FERRITIN LEVEL, CARDIAC AND HEPATIC T2-STAR MRI IN PATIENTS WITH MAJOR Β-THALASSEMIA. IRANIAN JOURNAL OF PEDIATRIC HEMATOLOGY AND ONCOLOGY[Internet]. 2014;4(1):17-21. Available from: https://sid.ir/paper/320618/en

IEEE: Copy

A. EGHBALI, H. TAHERAHMADI, M. SHAHBAZI, B. BAGHERI, and L. EBRAHIMI, “ASSOCIATION BETWEEN SERUM FERRITIN LEVEL, CARDIAC AND HEPATIC T2-STAR MRI IN PATIENTS WITH MAJOR Β-THALASSEMIA,” IRANIAN JOURNAL OF PEDIATRIC HEMATOLOGY AND ONCOLOGY, vol. 4, no. 1, pp. 17–21, 2014, [Online]. Available: https://sid.ir/paper/320618/en

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