EVALUATION OF THE EFFECT OF A PREOPERATIVE SINGLE DOSE OF GABAPENTIN ON EMERGENCE AGITATION IN PATIENTS UNDERGOING BREAST CANCER SURGERY

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

AZEMATI SIMIN; GHOLAMI DOKOUHAKI ABBAS; TALEI ABDOLRASOUL; KHADEMI SAEED; MOIN VAZIRI NADER

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: MIDDLE EAST JOURNAL OF CANCER Year:2013 | Volume:4 | Issue:4 Page(s): 139-143

Download Full-Text

View:

478

Download:

239

Cites:

Information Journal Paper

Title

EVALUATION OF THE EFFECT OF A PREOPERATIVE SINGLE DOSE OF GABAPENTIN ON EMERGENCE AGITATION IN PATIENTS UNDERGOING BREAST CANCER SURGERY

Author(s)

Keywords

GABAPENTIN

EMERGENCE AGITATION

POSTOPERATIVE PAIN

NAUSEA AND VOMITING

HEADACHE

DIZZINESS

Abstract

Background: EMERGENCE AGITATION is a transient confusional state that usually occurs within 10 to 30 minutes of recovery from general anesthesia. It may lead to serious consequences and increasing hospital costs. This study evaluates the effect of GABAPENTIN on EMERGENCE AGITATION in patients undergoing breast cancer surgery.Methods: This randomized, double blind controlled trial enrolled 100 female patients with American Society of Anesthesiologists' classifications I and II who were candidates for breast cancer surgery. Patients were randomly assigned into two groups (n=50) that received either oral GABAPENTIN 600 mg or placebo. Induction and maintenance of anesthesia were similar in both groups. At the end of surgery, patient' s agitation score, pain score, and presence of nausea or vomiting were reported. In the ward, the presence of HEADACHE or DIZZINESS was checked during the first 8 h. Mann-Whitney test was used for comparison of agitation and pain scores between two groups.Chi-square test was used for comparing occurrence of nausea, vomiting and qualitative.The qualitative demographic variable and t-test compared quantitative demographic variables.Results: There was a significantly lower incidence of EMERGENCE AGITATION in the GABAPENTIN group before (P<0.001) and after (P=0.029) extubation. There were significantly lower mean agitation scores before (P<001) and after (P=0.006) extubation and in the pain score (P=0.005) in the GABAPENTIN group. The need for remifentanil infusion (P<0.05) during surgery was significantly lower in the GABAPENTIN group compared with the placebo group. Occurrence of NAUSEA AND VOMITING and GABAPENTIN side effects that included HEADACHE or DIZZINESS did not significantly differ between two groups (P=0.126, P=1, P=0.629 respectively).Conclusion: GABAPENTIN not only decreased POSTOPERATIVE PAIN but also effectively reduced EMERGENCE AGITATION without any significant side effects in patients undergoing breast cancer surgery.

Cites

No record.

References

Cite

APA: Copy

AZEMATI, SIMIN, GHOLAMI DOKOUHAKI, ABBAS, TALEI, ABDOLRASOUL, KHADEMI, SAEED, & MOIN VAZIRI, NADER. (2013). EVALUATION OF THE EFFECT OF A PREOPERATIVE SINGLE DOSE OF GABAPENTIN ON EMERGENCE AGITATION IN PATIENTS UNDERGOING BREAST CANCER SURGERY. MIDDLE EAST JOURNAL OF CANCER, 4(4), 139-143. SID. https://sid.ir/paper/321070/en

Vancouver: Copy

AZEMATI SIMIN, GHOLAMI DOKOUHAKI ABBAS, TALEI ABDOLRASOUL, KHADEMI SAEED, MOIN VAZIRI NADER. EVALUATION OF THE EFFECT OF A PREOPERATIVE SINGLE DOSE OF GABAPENTIN ON EMERGENCE AGITATION IN PATIENTS UNDERGOING BREAST CANCER SURGERY. MIDDLE EAST JOURNAL OF CANCER[Internet]. 2013;4(4):139-143. Available from: https://sid.ir/paper/321070/en

IEEE: Copy

SIMIN AZEMATI, ABBAS GHOLAMI DOKOUHAKI, ABDOLRASOUL TALEI, SAEED KHADEMI, and NADER MOIN VAZIRI, “EVALUATION OF THE EFFECT OF A PREOPERATIVE SINGLE DOSE OF GABAPENTIN ON EMERGENCE AGITATION IN PATIENTS UNDERGOING BREAST CANCER SURGERY,” MIDDLE EAST JOURNAL OF CANCER, vol. 4, no. 4, pp. 139–143, 2013, [Online]. Available: https://sid.ir/paper/321070/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops