RELATION BETWEEN EDSS AND MONOSYMPTOMATIC OR POLYSYMPTOMATIC ONSET IN CLINICAL MANIFESTATIONS OF MULTIPLE SCLEROSIS IN BABOL, NORTHERN IRAN

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HOJJATI SEYED MOHAMMAD MASOOD; HOJJATI SEYYED ALI; BAES MOBINA; BIJANI ALI

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Journal: Caspian Journal of Internal Medicine Year:2014 | Volume:5 | Issue:1 Page(s): 5-8

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Title

RELATION BETWEEN EDSS AND MONOSYMPTOMATIC OR POLYSYMPTOMATIC ONSET IN CLINICAL MANIFESTATIONS OF MULTIPLE SCLEROSIS IN BABOL, NORTHERN IRAN

Author(s)

HOJJATI SEYED MOHAMMAD MASOOD | HOJJATI SEYYED ALI | BAES MOBINA | BIJANI ALI | Issue Writer Certificate

Keywords

MULTIPLE SCLEROSIS

MONOSYMPTOMATIC

POLYSYMPTOMATIC

Abstract

Background: POLYSYMPTOMATIC or MONOSYMPTOMATIC patients of MULTIPLE SCLEROSIS (MS) at the onset of the disease may influence the natural course of the disease. The purpose of this study was to determine the prognostic effect of the expanded disability status scale (EDSS) of patients with MS with POLYSYMPTOMATIC or MONOSYMPTOMATIC onset of the disease.Methods: From 2001 to 2011, 263 patients with definitive diagnosis of MS were investigated in Shahid Beheshti Teaching Hospital in Babol, Iran. These patients were assessed regarding mono-or poly symptoms at the beginning of their disease. MRI of brain and spinal cord was done for all cases. These cases were evaluated every three months interval. EDSS of each patient at the beginning of their disease and then yearly were evaluated and registered.Results: One hundred sixty-one subjects (61.2%) were MONOSYMPTOMATIC and 102 (38.8%) were POLYSYMPTOMATIC at the onset of their disease. The mean age of patients with MONOSYMPTOMATIC onset was 26.81+84 while in POLYSYMPTOMATIC was 26.35+7.7 years (P=0.656). Sex, place of residence and marriage statusbetween these two groups were equal. The mean EDSS in MONOSYMPTOMATIC and POLYSYMPTOMATIC patients were 1.37±0.64 and 2.16±0.714, respectively (P=0.0001). After the initiation of treatment, reduction of EDSS was seen in both groups but after the reduction in the first year, an increase of EDSS was seen in both groups. But there was no significant difference in the increase of EDSS in both groups.Conclusion: The results showed that the mean EDSS in MONOSYMPTOMATIC was lower than the POLYSYMPTOMATIC patients before treatment, but after treatment, this value does not differ in the increase of EDSS.

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APA: Copy

HOJJATI, SEYED MOHAMMAD MASOOD, HOJJATI, SEYYED ALI, BAES, MOBINA, & BIJANI, ALI. (2014). RELATION BETWEEN EDSS AND MONOSYMPTOMATIC OR POLYSYMPTOMATIC ONSET IN CLINICAL MANIFESTATIONS OF MULTIPLE SCLEROSIS IN BABOL, NORTHERN IRAN. CASPIAN JOURNAL OF INTERNAL MEDICINE, 5(1), 5-8. SID. https://sid.ir/paper/323343/en

Vancouver: Copy

HOJJATI SEYED MOHAMMAD MASOOD, HOJJATI SEYYED ALI, BAES MOBINA, BIJANI ALI. RELATION BETWEEN EDSS AND MONOSYMPTOMATIC OR POLYSYMPTOMATIC ONSET IN CLINICAL MANIFESTATIONS OF MULTIPLE SCLEROSIS IN BABOL, NORTHERN IRAN. CASPIAN JOURNAL OF INTERNAL MEDICINE[Internet]. 2014;5(1):5-8. Available from: https://sid.ir/paper/323343/en

IEEE: Copy

SEYED MOHAMMAD MASOOD HOJJATI, SEYYED ALI HOJJATI, MOBINA BAES, and ALI BIJANI, “RELATION BETWEEN EDSS AND MONOSYMPTOMATIC OR POLYSYMPTOMATIC ONSET IN CLINICAL MANIFESTATIONS OF MULTIPLE SCLEROSIS IN BABOL, NORTHERN IRAN,” CASPIAN JOURNAL OF INTERNAL MEDICINE, vol. 5, no. 1, pp. 5–8, 2014, [Online]. Available: https://sid.ir/paper/323343/en

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