Is 99m Tc-methylene diphosphonate bone scintigraphy a sensitive method for detecting bone lesions in multiple myeloma?

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VAKILI SADEGHI MOHSEN; SEDAGHAT SADEGH

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Journal Paper

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Journal: Caspian Journal of Internal Medicine Year:2018 | Volume:9 | Issue:2 Page(s): 140-143

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Title

Is 99m Tc-methylene diphosphonate bone scintigraphy a sensitive method for detecting bone lesions in multiple myeloma?

Author(s)

VAKILI SADEGHI MOHSEN | SEDAGHAT SADEGH | Issue Writer Certificate

Keywords

99m-Tc methylene diphosphonate

Bone lesion

Multiple myeloma

Abstract

Background: Bone lesion in Multiple myeloma (MM) is most commonly presented as a lytic lesion in this disease. Determination of extent of Bone lesions in MM is necessary to follow-up the patients. Whole body bone scan with 99m, Tc-methylene diphosphonate (MDP) has a lower sensitivity than other modalities. Methods: From the patients with MM admitted to Ayatollah Rouhani Hospital of Babol-Iran from 2009 to 2015, who had undergone whole body bone scan during diagnostic process, were entered into the study. Findings of bone scan were compared with MRI. Results: Of the 19 patients, sixteen (84. 2%) of them had positive finding in bone scan, fifteen (78. 9%) had MRI of the spine. While of the thirteen patients who had positive finding in MRI, seven (53. 8%) had more positive finding in thorcolumbosacral MRI than in bone scan. Conclusions: 99m-Tc MDP bone scan is a sensitive but insufficient method for detecting Bone lesions in MM.

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APA: Copy

VAKILI SADEGHI, MOHSEN, & SEDAGHAT, SADEGH. (2018). Is 99m Tc-methylene diphosphonate bone scintigraphy a sensitive method for detecting bone lesions in multiple myeloma?. CASPIAN JOURNAL OF INTERNAL MEDICINE, 9(2), 140-143. SID. https://sid.ir/paper/323513/en

Vancouver: Copy

VAKILI SADEGHI MOHSEN, SEDAGHAT SADEGH. Is 99m Tc-methylene diphosphonate bone scintigraphy a sensitive method for detecting bone lesions in multiple myeloma?. CASPIAN JOURNAL OF INTERNAL MEDICINE[Internet]. 2018;9(2):140-143. Available from: https://sid.ir/paper/323513/en

IEEE: Copy

MOHSEN VAKILI SADEGHI, and SADEGH SEDAGHAT, “Is 99m Tc-methylene diphosphonate bone scintigraphy a sensitive method for detecting bone lesions in multiple myeloma?,” CASPIAN JOURNAL OF INTERNAL MEDICINE, vol. 9, no. 2, pp. 140–143, 2018, [Online]. Available: https://sid.ir/paper/323513/en

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