Effect of hydroxyethyl starch on acidosis in patients with aluminum phosphide poisoning

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Kafi Gholamabbas; AKBARPOUR SAMANEH; AREFI MOHAMMAD; BEHNOUSH BEHNAM; AHMADI PISHKUHI MAHIN; Barzegari Nasrin

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Journal: Caspian Journal of Internal Medicine Year:2019 | Volume:10 | Issue:3 Page(s): 271-275

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Title

Effect of hydroxyethyl starch on acidosis in patients with aluminum phosphide poisoning

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Keywords

Hydroxyethyl Starch

Aluminum Phosphide

Rice tablet

Abstract

Background: Given the fact that various studies have reported the positive effects of Hydroxyethyl Starch therapy in controlling shock, this study aimed to compare the effects of Hydroxyethyl Starch on modifying acidosis and treating patients with Aluminum Phosphide poisoning. Methods: This was a randomized clinical trial that was conducted on 60 patients with Aluminum Phosphide poisoning. We compared the two groups of patients treated with Hydroxyethyl Starch and normal saline. Base excess and serum pH of arterial blood gases (ABG) were measured before and after the treatment and compared by t-test. Results: Results showed that arterial pH in the starch group and normal saline group increased by 0. 13 and 0. 18, respectively, and the difference between the two groups was not statistically significant. The difference in the base excess before and after treatment in the starch group and normal saline group was 6. 41 and 5. 39, respectively, and the difference between the two groups was not statistically significant. Changes in mean values of arterial pH after the intervention in comparison with before treatment were statistically significant (p<0. 05). Conclusion: Overall, the results of the present study show that starch is at least as effective as normal saline in treating acidosis in patients poisoned with Aluminum Phosphide and can be used instead of normal saline, and both of the two treatments could be equally effective.

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APA: Copy

Kafi, Gholamabbas, AKBARPOUR, SAMANEH, AREFI, MOHAMMAD, BEHNOUSH, BEHNAM, AHMADI PISHKUHI, MAHIN, & Barzegari, Nasrin. (2019). Effect of hydroxyethyl starch on acidosis in patients with aluminum phosphide poisoning. CASPIAN JOURNAL OF INTERNAL MEDICINE, 10(3), 271-275. SID. https://sid.ir/paper/323622/en

Vancouver: Copy

Kafi Gholamabbas, AKBARPOUR SAMANEH, AREFI MOHAMMAD, BEHNOUSH BEHNAM, AHMADI PISHKUHI MAHIN, Barzegari Nasrin. Effect of hydroxyethyl starch on acidosis in patients with aluminum phosphide poisoning. CASPIAN JOURNAL OF INTERNAL MEDICINE[Internet]. 2019;10(3):271-275. Available from: https://sid.ir/paper/323622/en

IEEE: Copy

Gholamabbas Kafi, SAMANEH AKBARPOUR, MOHAMMAD AREFI, BEHNAM BEHNOUSH, MAHIN AHMADI PISHKUHI, and Nasrin Barzegari, “Effect of hydroxyethyl starch on acidosis in patients with aluminum phosphide poisoning,” CASPIAN JOURNAL OF INTERNAL MEDICINE, vol. 10, no. 3, pp. 271–275, 2019, [Online]. Available: https://sid.ir/paper/323622/en

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