EFFECT OF VITAMIN C ON STYRENE INDUCED RESPIRATORY TOXICITY

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

AHMADIZADEH MASSUMEH; POL TAYEBEH; BOAZAR MOHAMAD

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: International Journal of Occupational Hygiene Year:2011 | Volume:3 | Issue:2 Page(s): 76-80

Download Full-Text

View:

298

Download:

Cites:

Information Journal Paper

Title

EFFECT OF VITAMIN C ON STYRENE INDUCED RESPIRATORY TOXICITY

Author(s)

AHMADIZADEH MASSUMEH | POL TAYEBEH | BOAZAR MOHAMAD | Issue Writer Certificate

Keywords

STYRENE VITAMIN C

LUNG

TRACHEA

RAT

Abstract

Styrene (ethylbenzene) is widely used as a solvent in many industrial setting. Occupational exposure to ST can result in pulmonary toxicity. For better understanding of the mechanism by which styrene caused LUNG injury, this study was undertaken to investigate the effect of styrene on RAT respiratory epithelial cells. The role of vitamin C (Vit C) on styrene induced toxicity was also investigated. Adult male RATs were given ST (ip) at doses of 0, 200, 400 or 600 mg/kg. Another series of RATs were pretreated with Vit C (300 mg/kg, ip) 30 min prior administration of various doses of ST. 24 h later, animals were killed with overdose of sodium pentobarbital. LUNG and TRACHEA tissues were removed, fixed and processed for light microscopy. Results demonstrated that styrene induced dose-dependant injury in respiratory epithelial cells. The antioxidant, Vit C protected cells against styrene toxicity. The results support the view that generation of oxidative stress is responsible for ST-induced damage in respiratory airway. The finding that Vit C has potential to protect respiratory epithelial cells against ST toxicity further support this hypothesis.

Cites

THE PREVENTIVE EFFECT OF VITAMIN C ON STYRENE-INDUCED TOXICITY IN RAT LIVER AND KIDNEY

References

No record.

Cite

APA: Copy

AHMADIZADEH, MASSUMEH, POL, TAYEBEH, & BOAZAR, MOHAMAD. (2011). EFFECT OF VITAMIN C ON STYRENE INDUCED RESPIRATORY TOXICITY. INTERNATIONAL JOURNAL OF OCCUPATIONAL HYGIENE, 3(2), 76-80. SID. https://sid.ir/paper/324019/en

Vancouver: Copy

AHMADIZADEH MASSUMEH, POL TAYEBEH, BOAZAR MOHAMAD. EFFECT OF VITAMIN C ON STYRENE INDUCED RESPIRATORY TOXICITY. INTERNATIONAL JOURNAL OF OCCUPATIONAL HYGIENE[Internet]. 2011;3(2):76-80. Available from: https://sid.ir/paper/324019/en

IEEE: Copy

MASSUMEH AHMADIZADEH, TAYEBEH POL, and MOHAMAD BOAZAR, “EFFECT OF VITAMIN C ON STYRENE INDUCED RESPIRATORY TOXICITY,” INTERNATIONAL JOURNAL OF OCCUPATIONAL HYGIENE, vol. 3, no. 2, pp. 76–80, 2011, [Online]. Available: https://sid.ir/paper/324019/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops