THE ROLE OF ASCORBIC ACID IN THE PREVENTION OF ATRIAL FIBRILLATION AFTER ELECTIVE ON PUMP MYOCARDIAL REVASCULARIZATION SURGERY: A SINGLE CENTER EXPERIENCE-PILOT STUDY

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BAGHAEI R.

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Journal: IRANIAN JOURNAL OF CARDIAC SURGERY Year:2011 | Volume:3 | Issue:1 Page(s): 48-49

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Title

THE ROLE OF ASCORBIC ACID IN THE PREVENTION OF ATRIAL FIBRILLATION AFTER ELECTIVE ON PUMP MYOCARDIAL REVASCULARIZATION SURGERY: A SINGLE CENTER EXPERIENCE-PILOT STUDY

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BAGHAEI R.

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Abstract

Atrial fibrillation (AF) is a common arrhythmia that occurs postoperatively in cardiac surgery. There is evidence for the role of oxidative stress in the etiology of AF. In our study, we examined whether antioxidant ascorbic acid (vitamin C), could help in the reduction of the incidence of postoperative AF. Patients who were scheduled to undergo elective isolated on-pump coronary artery bypass grafting (CABG) were included in our study. One hundred and seventy patients were randomly divided in two groups: Group A (n=85) received vitamin C preoperatively and postoperatively whereas Group B (n=85) did not receive any (control group). The incidence of AF was 44.7% in the vitamin C group and 61.2% in the control group (P=0.041). The hospitalization time, the intensive care unit stay and the time interval for the conversion of AF into sinus rhythm was significantly shorter in the vitamin C group. Patients that developed AF also had longer hospital length of stay (9.5±2.8 days vs. 6.7±1.9, P=0.034). Supplementation of vitamin C reduces the incidence of post CABG AF, and decreases the time needed for rhythm restoration and length of hospital stay. Keywords: Post CABG atrial fibrillation; Oxidative stress; Ascorbic acid; Vitamin C class I or II, and 61.2% had some degree of persistent mitral regurgitation or stenosis, despite stable hemodynamics. Stenosis is a statistically significant risk factor for surgical intervention at less than 1 year of age and is related to higher overall mortality and incidence of late cardiac failure and mitral dysfunction; parachute mitral valve is related to higher mortality and morbidity.Conclusions: Mitral valve repair shows acceptable early mortality and reoperation rates. Mitral malformations in the complex group are related to a significantly higher risk of reoperation on the mitral valve. Parachute mitral valve is associated with a higher rate of early mortality.

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APA: Copy

BAGHAEI, R.. (2011). THE ROLE OF ASCORBIC ACID IN THE PREVENTION OF ATRIAL FIBRILLATION AFTER ELECTIVE ON PUMP MYOCARDIAL REVASCULARIZATION SURGERY: A SINGLE CENTER EXPERIENCE-PILOT STUDY. IRANIAN JOURNAL OF CARDIAC SURGERY, 3(1), 48-49. SID. https://sid.ir/paper/324120/en

Vancouver: Copy

BAGHAEI R.. THE ROLE OF ASCORBIC ACID IN THE PREVENTION OF ATRIAL FIBRILLATION AFTER ELECTIVE ON PUMP MYOCARDIAL REVASCULARIZATION SURGERY: A SINGLE CENTER EXPERIENCE-PILOT STUDY. IRANIAN JOURNAL OF CARDIAC SURGERY[Internet]. 2011;3(1):48-49. Available from: https://sid.ir/paper/324120/en

IEEE: Copy

R. BAGHAEI, “THE ROLE OF ASCORBIC ACID IN THE PREVENTION OF ATRIAL FIBRILLATION AFTER ELECTIVE ON PUMP MYOCARDIAL REVASCULARIZATION SURGERY: A SINGLE CENTER EXPERIENCE-PILOT STUDY,” IRANIAN JOURNAL OF CARDIAC SURGERY, vol. 3, no. 1, pp. 48–49, 2011, [Online]. Available: https://sid.ir/paper/324120/en

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