IS ADVANCED AGE A CONTRAINDICATION FOR EMERGENT REPAIR OF ACUTE TYPE A AORTIC DISSECTION?

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BAGHAEI R.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

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Journal: Iranian Journal of Toxicology Year:2010 | Volume:3 | Issue:5 Page(s): 22-22

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Title

IS ADVANCED AGE A CONTRAINDICATION FOR EMERGENT REPAIR OF ACUTE TYPE A AORTIC DISSECTION?

Author(s)

BAGHAEI R.

Keywords

MORBIDITY

OUTCOMES

MORTALITY

AORTIC DISSECTION

Abstract

With the general increase in human lifespan, cardiac surgeons are faced with treating an increasing number of elderly patients. The aim of our study was to investigate whether advanced age poses an increased risk for major MORBIDITY and MORTALITY with repair of acute type A AORTIC DISSECTION. Between 2000 and 2008, 119 patients underwent emergency operation for acute type A AORTIC DISSECTION at two institutions; 90 were younger than 70 years of age and 29 patients were 70 years or older. Major MORBIDITY, operative and 5-year actuarial survival were compared between groups. The operative MORTALITY rates were comparable between the two groups (18.9% in patients <70 years vs. 24.1% for patients 70 years, P=0.6). There was no difference in the rates of reoperation for bleeding (<70 years 31.7% vs. 14.3% for 70 years, P=0.09), stroke (18.9% for those <70 years vs. 20.7% for those 70 years, P=0.79), acute renal failure (22.2% for those <70 years vs. 17.2% for those 70 years, P=0.79) or prolonged ventilation (34.4% for those <70 years vs. 24.1% for those 70 years, P=0.36) between the two groups. Actuarial 5-year survival rates were 77% for patients <70 years vs. 59% for patients 70 years (P=0.07). The MORTALITY for patients who presented with hemodynamic instability was markedly higher (10 out of 14 patients, 71.4%) compared with the MORTALITY of those who presented with stable hemodynamics (21 out of 88 patients, 23.9%, P<0.001), regardless of age group. No significant differences in operative MORTALITY, major MORBIDITY and actuarial 5-year survival were observed between patients 70 years and younger patients although there was a trend toward a lower actuarial 5-year survival in older patients. Surgery for type A acute AORTIC DISSECTION in patients 70 years or older can be performed with acceptable OUTCOMES. Hemodynamic instability portends a poor prognosis, regardless of age.

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APA: Copy

BAGHAEI, R.. (2010). IS ADVANCED AGE A CONTRAINDICATION FOR EMERGENT REPAIR OF ACUTE TYPE A AORTIC DISSECTION?. IRANIAN JOURNAL OF TOXICOLOGY, 3(5), 22-22. SID. https://sid.ir/paper/324155/en

Vancouver: Copy

BAGHAEI R.. IS ADVANCED AGE A CONTRAINDICATION FOR EMERGENT REPAIR OF ACUTE TYPE A AORTIC DISSECTION?. IRANIAN JOURNAL OF TOXICOLOGY[Internet]. 2010;3(5):22-22. Available from: https://sid.ir/paper/324155/en

IEEE: Copy

R. BAGHAEI, “IS ADVANCED AGE A CONTRAINDICATION FOR EMERGENT REPAIR OF ACUTE TYPE A AORTIC DISSECTION?,” IRANIAN JOURNAL OF TOXICOLOGY, vol. 3, no. 5, pp. 22–22, 2010, [Online]. Available: https://sid.ir/paper/324155/en

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