CORONARY ARTERY BYPASS GRAFTING IN FAMILIAL HYPERCHOLESTEROLEMIA

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BAGHAEI RAMIN; JALILLIFAR NASER; REZAEI MIKAEAL; DEHESTANI ALIREZA; VAFAEI HAMIDREZA

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Journal: IRANIAN JOURNAL OF CARDIAC SURGERY Year:2010 | Volume:3 | Issue:5 Page(s): 3-5

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Title

CORONARY ARTERY BYPASS GRAFTING IN FAMILIAL HYPERCHOLESTEROLEMIA

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Keywords

FAMILIAL HYPERCHOLESTEROLEMIA

CORONARY ARTERY BYPASS GRAFTING

Abstract

Objectives: FAMILIAL HYPERCHOLESTEROLEMIA is dominantly inherited disorder caused mutation by at the locus for the low-density lipoprotein receptor and is frequently associated with premature coronary artery disease. This study was performed to determine outcomes of CORONARY ARTERY BYPASS GRAFTING for patients with FAMILIAL HYPERCHOLESTEROLEMIA.Methods: During the past 7 years, 11 from 12 patients with heterozygous FAMILIAL HYPERCHOLESTEROLEMIA underwent primary CORONARY ARTERY BYPASS GRAFTING and 1 from 12 patients underwent PCI without hospital death. All patients received one internal thoracic artery graft and supplemental vein grafts. After operation all patients received diet therapy and intensive cholesterol-lowering therapy. 4 patients received low density lipoprotein aphaeresis. Results: Both groups were similar regarding During follow up period (range 1 to 84 months, mean 16 months) there was no cardiac death but 2 of them had recurrent disease. Inspite of severe coronary atherosclerosis, these patients with FAMILIAL HYPERCHOLESTEROLEMIA showed good short term outcomes after coronary artery bypass surgery.Conclusion: The present finding suggests that aggressive use of arterial and venous grafts, intensive cholesterol-lowering therapy and low-density lipoprotein aphaeresis may be useful in patients with FAMILIAL HYPERCHOLESTEROLEMIA.

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APA: Copy

BAGHAEI, RAMIN, JALILLIFAR, NASER, REZAEI, MIKAEAL, DEHESTANI, ALIREZA, & VAFAEI, HAMIDREZA. (2010). CORONARY ARTERY BYPASS GRAFTING IN FAMILIAL HYPERCHOLESTEROLEMIA. IRANIAN JOURNAL OF CARDIAC SURGERY, 3(5), 3-5. SID. https://sid.ir/paper/324156/en

Vancouver: Copy

BAGHAEI RAMIN, JALILLIFAR NASER, REZAEI MIKAEAL, DEHESTANI ALIREZA, VAFAEI HAMIDREZA. CORONARY ARTERY BYPASS GRAFTING IN FAMILIAL HYPERCHOLESTEROLEMIA. IRANIAN JOURNAL OF CARDIAC SURGERY[Internet]. 2010;3(5):3-5. Available from: https://sid.ir/paper/324156/en

IEEE: Copy

RAMIN BAGHAEI, NASER JALILLIFAR, MIKAEAL REZAEI, ALIREZA DEHESTANI, and HAMIDREZA VAFAEI, “CORONARY ARTERY BYPASS GRAFTING IN FAMILIAL HYPERCHOLESTEROLEMIA,” IRANIAN JOURNAL OF CARDIAC SURGERY, vol. 3, no. 5, pp. 3–5, 2010, [Online]. Available: https://sid.ir/paper/324156/en

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