DETERMINING THE COMPLICATIONS, MORTALITY, AND TREATMENT OF PATIENTS HOSPITALIZED AT BAHARLOO HOSPITAL DUE TO ORAL HYPOGLYCEMIC DRUGS TOXICITY IN 2008-9

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

BEHNOOSH BEHNAM; TAGHDOSI NEJAD FAKHRODIN; AREFI MOHAMMAD; ROSHANI RASOUL; JAMALIAN MOHAMMAD

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: IRANIAN JOURNAL OF TOXICOLOGY Year:2011 | Volume:4 | Issue:4 (11) Page(s): 367-372

Download Full-Text

View:

302

Download:

Cites:

Information Journal Paper

Title

DETERMINING THE COMPLICATIONS, MORTALITY, AND TREATMENT OF PATIENTS HOSPITALIZED AT BAHARLOO HOSPITAL DUE TO ORAL HYPOGLYCEMIC DRUGS TOXICITY IN 2008-9

Author(s)

Keywords

GLYBENCLAMIDE

METFORMIN

ORAL HYPOGLYCEMIC DRUGS

SUICIDE

TOXICITY

Abstract

Background: GLYBENCLAMIDE and METFORMIN are two of the most common ORAL HYPOGLYCEMIC DRUGS which are often used in treatment of type II diabetes mellitus. TOXICITY due to these drugs may occur intentionally, accidentally, or even at the normal dosage because of the progression of such internal diseases as renal dysfunction.Methods: In this case series study, 59 patients poisoned with oral hypoglycemic agents referring to Baharloo Hospital were evaluated between March 2009 and September 2010.Results: The most common clinical findings were lethargy (66.7%) and drowsiness (66.7%) that were mostly observed in patients who had concomitantly ingested GLYBENCLAMIDE and METFORMIN.Metabolic acidosis was observed in 33.3% of the patients who had ingested METFORMIN alone and 22.2 % of the patients who had ingested METFORMIN together with GLYBENCLAMIDE. Some degrees of hypoglycemia were observed in 50.8% of the patients upon admission; nevertheless, severe hypoglycemia was seen only in 17% of them. The majority of the patients got improved within 3 days of hospitalization and got discharged.Although due to the severity of TOXICITY and its associated complications, 22.8% of the patients needed more than 3 days of hospitalization, permanent neurological complications and mortality did not happen to any of the patients.Conclusion: GLYBENCLAMIDE overdose leads to hypoglycemia and it can be prevented by careful monitoring of blood glucose and immediate treatment with intravenous dextrose, mostly occuring due to its hypoglycemic effects on the brain.

Cites

No record.

References

No record.

Cite

APA: Copy

BEHNOOSH, BEHNAM, TAGHDOSI NEJAD, FAKHRODIN, AREFI, MOHAMMAD, ROSHANI, RASOUL, & JAMALIAN, MOHAMMAD. (2011). DETERMINING THE COMPLICATIONS, MORTALITY, AND TREATMENT OF PATIENTS HOSPITALIZED AT BAHARLOO HOSPITAL DUE TO ORAL HYPOGLYCEMIC DRUGS TOXICITY IN 2008-9. IRANIAN JOURNAL OF TOXICOLOGY, 4(4 (11)), 367-372. SID. https://sid.ir/paper/324258/en

Vancouver: Copy

BEHNOOSH BEHNAM, TAGHDOSI NEJAD FAKHRODIN, AREFI MOHAMMAD, ROSHANI RASOUL, JAMALIAN MOHAMMAD. DETERMINING THE COMPLICATIONS, MORTALITY, AND TREATMENT OF PATIENTS HOSPITALIZED AT BAHARLOO HOSPITAL DUE TO ORAL HYPOGLYCEMIC DRUGS TOXICITY IN 2008-9. IRANIAN JOURNAL OF TOXICOLOGY[Internet]. 2011;4(4 (11)):367-372. Available from: https://sid.ir/paper/324258/en

IEEE: Copy

BEHNAM BEHNOOSH, FAKHRODIN TAGHDOSI NEJAD, MOHAMMAD AREFI, RASOUL ROSHANI, and MOHAMMAD JAMALIAN, “DETERMINING THE COMPLICATIONS, MORTALITY, AND TREATMENT OF PATIENTS HOSPITALIZED AT BAHARLOO HOSPITAL DUE TO ORAL HYPOGLYCEMIC DRUGS TOXICITY IN 2008-9,” IRANIAN JOURNAL OF TOXICOLOGY, vol. 4, no. 4 (11), pp. 367–372, 2011, [Online]. Available: https://sid.ir/paper/324258/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops