Metabolic analysis of acute appendicitis by using system biology approach

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ZOJAJI HOMAYOUN; REZAEI TAVIRANI MAJID; MANSOURI VAHID; Seyed Salehi Ali; MAHMOUD ROBATI REZA; Lak Elena

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Journal Paper

Paper Information

Journal: Gastroenterology and Hepatology From Bed to Bench Year:2018 | Volume:11 | Issue:suppl 1 Page(s): 92-97

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Title

Metabolic analysis of acute appendicitis by using system biology approach

Author(s)

Keywords

Appendicitis

Gene

Biomarker

Abstract

Aim: Introducing possible suitable compound as diagnostic agent in Appendicitis is aim of this investigation. Background: Appendicitis diagnosis is a difficult step in treatment of disease due to complex abdominal pain signal which may be refer to the non-Appendicitis pain. Methods: Gene expression profiles of children with non-preforated Appendicitis in comparison with the samples with nonAppendicitis abdominal pain are analysis via protein – protein interaction (PPI) and the critical compounds are introduced by STITCH. Results: Ten compounds including including MgATP, glycerol, MgADP, calcium ions, chloride, magnesium, phosphate, sulphate, acetate, and sodium are introduced as possible Biomarker panel to differentiate Appendicitis from the other abdominal pains. Conclusion: A laboratory method such as flame photometry based on metal detection for diagnosis of Appendicitis is possible, however more investigations are required.

Cites

Introducing Serine as Cardiovascular Disease Biomarker Candidate via Pathway Analysis

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APA: Copy

ZOJAJI, HOMAYOUN, REZAEI TAVIRANI, MAJID, MANSOURI, VAHID, Seyed Salehi, Ali, MAHMOUD ROBATI, REZA, & Lak, Elena. (2018). Metabolic analysis of acute appendicitis by using system biology approach. GASTROENTEROLOGY AND HEPATOLOGY FROM BED TO BENCH, 11(suppl 1), 92-97. SID. https://sid.ir/paper/324826/en

Vancouver: Copy

ZOJAJI HOMAYOUN, REZAEI TAVIRANI MAJID, MANSOURI VAHID, Seyed Salehi Ali, MAHMOUD ROBATI REZA, Lak Elena. Metabolic analysis of acute appendicitis by using system biology approach. GASTROENTEROLOGY AND HEPATOLOGY FROM BED TO BENCH[Internet]. 2018;11(suppl 1):92-97. Available from: https://sid.ir/paper/324826/en

IEEE: Copy

HOMAYOUN ZOJAJI, MAJID REZAEI TAVIRANI, VAHID MANSOURI, Ali Seyed Salehi, REZA MAHMOUD ROBATI, and Elena Lak, “Metabolic analysis of acute appendicitis by using system biology approach,” GASTROENTEROLOGY AND HEPATOLOGY FROM BED TO BENCH, vol. 11, no. suppl 1, pp. 92–97, 2018, [Online]. Available: https://sid.ir/paper/324826/en

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