Changing the cause of liver cirrhosis from hepatitis B virus to fatty liver in Iranian patients

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HATAMI BEHZAD; ASHTARI SARA; SHARIFIAN AFSANEH; RAHMANI SERAJI HAMIDEH; khalili Elmira; HATAMI YASIN; ZALI MOHAMMAD REZA

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Journal: Gastroenterology and Hepatology From Bed to Bench Year:2017 | Volume:10 | Issue:Suppl 1 Page(s): 20-26

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Title

Changing the cause of liver cirrhosis from hepatitis B virus to fatty liver in Iranian patients

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Keywords

Liver cirrhosis

Etiology

Epidemiology

Iran

Abstract

Aim: The objective of this study was to determine the epidemiologic characteristics of patients with Liver cirrhosis. Background: Liver cirrhosis is an end-stage condition of chronic liver disease. Liver disease is an important cause of morbidity and mortality worldwide. Methods: In this cross-sectional study, demographic and epidemiologic characteristics of 203 patients with Liver cirrhosis who were admitted in Taleghani Hospital over a period of two years were determined. Results: A total of 203 patients with Liver cirrhosis consisted of 136 (67%) males and 67 (33%) females and the mean age was 53. 7± 15. 2 years. No Etiology were found in (59. 6%) cirrhotic patients; therefore, they were labeled as cryptogenic cirrhosis, but according to clinical evidence and ultrasonography findings, (29. 7%) of these patients were probable NAFLD. The other causes of Liver cirrhosis in this study were HBV (20. 2%), HCV (11. 8%) and autoimmune hepatitis (AIH) (8. 4%), respectively. Esophageal varices were present in (41. 9%), ascites in (36. 5%), variceal bleeding in (8. 9%), encephalopathy in (7. 4%) and spontaneous bacterial peritonitis (SBP) in (5. 4%) of patients. When cirrhotic patients were grouped according to Child-Pugh classification, 26. 1%, 54. 7% and 19. 2% were in classes A, B and C respectively. The mean MELD score was 16. 16± 7. 7. Conclusion: In this study we found that the leading Etiology of cirrhosis is cryptogenic cirrhosis 59. 6% (in all age groups) and followed by HBV. Noteworthy, according to the clinical and ultrasonography findings, 29. 7% of patients who were labeled as cryptogenic cirrhosis were consistent with NAFLD.

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APA: Copy

HATAMI, BEHZAD, ASHTARI, SARA, SHARIFIAN, AFSANEH, RAHMANI SERAJI, HAMIDEH, khalili, Elmira, HATAMI, YASIN, & ZALI, MOHAMMAD REZA. (2017). Changing the cause of liver cirrhosis from hepatitis B virus to fatty liver in Iranian patients. GASTROENTEROLOGY AND HEPATOLOGY FROM BED TO BENCH, 10(Suppl 1), 20-26. SID. https://sid.ir/paper/324903/en

Vancouver: Copy

HATAMI BEHZAD, ASHTARI SARA, SHARIFIAN AFSANEH, RAHMANI SERAJI HAMIDEH, khalili Elmira, HATAMI YASIN, ZALI MOHAMMAD REZA. Changing the cause of liver cirrhosis from hepatitis B virus to fatty liver in Iranian patients. GASTROENTEROLOGY AND HEPATOLOGY FROM BED TO BENCH[Internet]. 2017;10(Suppl 1):20-26. Available from: https://sid.ir/paper/324903/en

IEEE: Copy

BEHZAD HATAMI, SARA ASHTARI, AFSANEH SHARIFIAN, HAMIDEH RAHMANI SERAJI, Elmira khalili, YASIN HATAMI, and MOHAMMAD REZA ZALI, “Changing the cause of liver cirrhosis from hepatitis B virus to fatty liver in Iranian patients,” GASTROENTEROLOGY AND HEPATOLOGY FROM BED TO BENCH, vol. 10, no. Suppl 1, pp. 20–26, 2017, [Online]. Available: https://sid.ir/paper/324903/en

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