REVIEW OF AUTO-FLUORESCENT EFFECT ON DIAGNOSIS OF ORAL MALIGNANT AND PRE-MALIGNANT LESIONS

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SEHATPOUR ALIYE; SEHATPOUR MARZIYEH

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Paper Information

Journal: JOURNAL OF LASERS IN MEDICAL SCIENCES Year:2018 | Volume:9 | Issue:SUPPL A (9TH WORLD CONGRESS OF SOLA) Page(s): 58-58

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Title

REVIEW OF AUTO-FLUORESCENT EFFECT ON DIAGNOSIS OF ORAL MALIGNANT AND PRE-MALIGNANT LESIONS

Author(s)

SEHATPOUR ALIYE | SEHATPOUR MARZIYEH

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Abstract

Background: Genetically altered cells could become widespread across the epithelium of patients with oral cancer, often, in clinically and histologically normal tissue and contribute to recurrent disease. Auto-fluorescence imaging has immerged as a promising technology to aid clinicians in screening for oral neoplasia and as an aid to resection. Tissue optics could further extend our understanding of alteration to phenotype as a result of molecular changes.Methods: Fifteen papers were found in a research conducted in the PubMed search engine with key word: fluorescent, oral, malignant and premalignant from 1996 to 2017.Results: By using a handheld device in the operating room in patient with histologically confirmed neoplasia, fluorescent visualization (FV) decreased. In the most dysplastic lesions, FV loss extended in at least one direction beyond the clinically visible tumor. Molecular analysis on margins with low grade or no dysplasia showed a significant association of LOH (loss of heterozygosity) in FVL (fluorescent visualization loss) biopsies, with LOH at 3p and/ or 9p (previously associated with local tumor recurrence).Conclusion: The data have shown that direct FV can identify subclinical high-risk fields with cancerous and precancerous changes in the operating room setting.

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APA: Copy

SEHATPOUR, ALIYE, & SEHATPOUR, MARZIYEH. (2018). REVIEW OF AUTO-FLUORESCENT EFFECT ON DIAGNOSIS OF ORAL MALIGNANT AND PRE-MALIGNANT LESIONS. JOURNAL OF LASERS IN MEDICAL SCIENCES, 9(SUPPL A (9TH WORLD CONGRESS OF SOLA)), 58-58. SID. https://sid.ir/paper/326069/en

Vancouver: Copy

SEHATPOUR ALIYE, SEHATPOUR MARZIYEH. REVIEW OF AUTO-FLUORESCENT EFFECT ON DIAGNOSIS OF ORAL MALIGNANT AND PRE-MALIGNANT LESIONS. JOURNAL OF LASERS IN MEDICAL SCIENCES[Internet]. 2018;9(SUPPL A (9TH WORLD CONGRESS OF SOLA)):58-58. Available from: https://sid.ir/paper/326069/en

IEEE: Copy

ALIYE SEHATPOUR, and MARZIYEH SEHATPOUR, “REVIEW OF AUTO-FLUORESCENT EFFECT ON DIAGNOSIS OF ORAL MALIGNANT AND PRE-MALIGNANT LESIONS,” JOURNAL OF LASERS IN MEDICAL SCIENCES, vol. 9, no. SUPPL A (9TH WORLD CONGRESS OF SOLA), pp. 58–58, 2018, [Online]. Available: https://sid.ir/paper/326069/en

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