CHEMICAL COMPOSITION, ANTIMICROBIAL ACTIVITY AND ANTIVIRAL ACTIVITY OF ESSENTIAL OIL OF CARUM COPTICUM FROM IRAN

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KAZEMI OSKUEE REZA; BEHRAVAN JAVAD; RAMEZANI MOHAMMAD

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Journal Paper

Paper Information

Journal: Avicenna Journal of Phytomedicine Year:2011 | Volume:1 | Issue:2 Page(s): 83-90

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Title

CHEMICAL COMPOSITION, ANTIMICROBIAL ACTIVITY AND ANTIVIRAL ACTIVITY OF ESSENTIAL OIL OF CARUM COPTICUM FROM IRAN

Author(s)

KAZEMI OSKUEE REZA | BEHRAVAN JAVAD | RAMEZANI MOHAMMAD | Issue Writer Certificate

Keywords

CARUM COPTICUM

CHEMICAL COMPOSITION

ESSENTIAL OIL

ANTIMICROBIAL ACTIVITY

ANTIVIRAL ACTIVITY

Abstract

Objectives: Evaluation of therapeutic effects of CARUM COPTICUM (C. copticum) has been the subject of several studies in recent years. Thymol the major component of C. copticum is a widely known anti-microbial agent. In this study, the antibacterial and anti-viral activities of ESSENTIAL OIL of C. copticum fruit were determined.Materials and Methods: ESSENTIAL OIL of C. copticum was analyzed by means of gas chromatography-mass spectrometry (GC-MS). The ANTIMICROBIAL ACTIVITY of the oil was evaluated against six Gram (+/-) bacteria and fungi, using the micro broth dilution technique. ANTIVIRAL ACTIVITY of the ESSENTIAL OIL was evaluated using a Bacillus phage CP51.Results: From the ten identified constituents, representing 98.7% of the oil, thymol (72.3%), terpinolene (13.12%) and o-cymene (11.97%) were the major components. It was found that the oil exhibited strong ANTIMICROBIAL ACTIVITY against Staphylococcus aureus (S. aureus) and Bacillus subtilis (B. subtilis) (MIC, 0.00025% v/v). Furthermore, the ANTIVIRAL ACTIVITY of the oil was evaluated by plaque reduction assay.Conclusion: The ESSENTIAL OIL showed an ANTIVIRAL ACTIVITY against phage when phage was pre-incubated with the ESSENTIAL OIL prior to its exposure to B. cereus and without any pre-incubation with the phage, suggesting that the oil directly inactivated virus particles.

Cites

IN VITRO ANTI-TOXOPLASMA EFFECTS OF ETHANOLIC EXTRACTS OF ARTEMISIA ABSINTHIUM L., CARUM COPTICUM L. AND GOSSYPIUM HIRSUTUM

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APA: Copy

KAZEMI OSKUEE, REZA, BEHRAVAN, JAVAD, & RAMEZANI, MOHAMMAD. (2011). CHEMICAL COMPOSITION, ANTIMICROBIAL ACTIVITY AND ANTIVIRAL ACTIVITY OF ESSENTIAL OIL OF CARUM COPTICUM FROM IRAN. AVICENNA JOURNAL OF PHYTOMEDICINE (AJP), 1(2), 83-90. SID. https://sid.ir/paper/326232/en

Vancouver: Copy

KAZEMI OSKUEE REZA, BEHRAVAN JAVAD, RAMEZANI MOHAMMAD. CHEMICAL COMPOSITION, ANTIMICROBIAL ACTIVITY AND ANTIVIRAL ACTIVITY OF ESSENTIAL OIL OF CARUM COPTICUM FROM IRAN. AVICENNA JOURNAL OF PHYTOMEDICINE (AJP)[Internet]. 2011;1(2):83-90. Available from: https://sid.ir/paper/326232/en

IEEE: Copy

REZA KAZEMI OSKUEE, JAVAD BEHRAVAN, and MOHAMMAD RAMEZANI, “CHEMICAL COMPOSITION, ANTIMICROBIAL ACTIVITY AND ANTIVIRAL ACTIVITY OF ESSENTIAL OIL OF CARUM COPTICUM FROM IRAN,” AVICENNA JOURNAL OF PHYTOMEDICINE (AJP), vol. 1, no. 2, pp. 83–90, 2011, [Online]. Available: https://sid.ir/paper/326232/en

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