FORMULATION OF SPIRONOLACTONE CREAM AND COMPARATIVE EVALUATION OF ORAL AND LOCAL SPIRONOLACTONE EFFICACY IN MANAGEMENT OF HIRSUTISM

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

SHOHRATI M.; DAVOUDI SEYED MASOUD; SADR S.B.; JAHANDIDEH H.; SABOURI YAZDI SH.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: KOWSAR MEDICAL JOURNAL Year:2006 | Volume:11 | Issue:3 Page(s): 235-239

Download Full-Text

Persian Verion

View:

6,186

Download:

Cites:

Information Journal Paper

Title

FORMULATION OF SPIRONOLACTONE CREAM AND COMPARATIVE EVALUATION OF ORAL AND LOCAL SPIRONOLACTONE EFFICACY IN MANAGEMENT OF HIRSUTISM

Author(s)

Keywords

HIRSUTISMQ3

SPIRONOLACTONEQ4

SIDE EFFECTQ3

CREAMQ3

TABLETABSTRACTQ3

Abstract

Objective: The aim of this study was evaluation the formulation of SPIRONOLACTONE CREAM and comparative evaluation of oral and local SPIRONOLACTONE efficacy in management of HIRSUTISM.Materials and Methods: 77 patients with HIRSUTISM were randomized to use SPIRONOLACTONE CREAM (n=39) or SPIRONOLACTONE tablets (n=38). Before beginning the study, HIRSUTISM scores of both groups were measured and no significant difference was observed between them. All the patients used their medications for 7 months and were visited by a dermatologist monthly. After the course of treatment, the HIRSUTISM score was measured for all of them and compared with the base score at the beginning of the treatment.Results: Among tablet-receiving patients, in 15.8% HIRSUTISM score significantly decreased (p<0.05). In 44.7% there was a non-significant decrease iri HIRSUTISM score and the scores in 39.5% of them didn't change.In contrast, 55.8% of patients used SPIRONOLACTONE CREAM, had significant decrease in their HIRSUTISM score and in the rest of the patients of this group, although the scores decreased, it was not significant. In CREAM-receiving patients, no one experienced SIDE EFFECTs while in patients took oral SPIRONOLACTONE, drug adverse effects including headache, nausea and menstrual dysfunction were seen in 40% of cases.Conclusion: Using SPIRONOLACTONE CREAM compared with tablet was associated with significant decrease of HIRSUTISM score and less SIDE EFFECTs. As HIRSUTISM needs a long term therapy, it seems that local therapy with CREAM is much better in treating hirsute patients.

Cites

No record.

References

No record.

Cite

APA: Copy

SHOHRATI, M., DAVOUDI, SEYED MASOUD, SADR, S.B., JAHANDIDEH, H., & SABOURI YAZDI, SH.. (2006). FORMULATION OF SPIRONOLACTONE CREAM AND COMPARATIVE EVALUATION OF ORAL AND LOCAL SPIRONOLACTONE EFFICACY IN MANAGEMENT OF HIRSUTISM. KOWSAR MEDICAL JOURNAL, 11(3), 235-239. SID. https://sid.ir/paper/32720/en

Vancouver: Copy

SHOHRATI M., DAVOUDI SEYED MASOUD, SADR S.B., JAHANDIDEH H., SABOURI YAZDI SH.. FORMULATION OF SPIRONOLACTONE CREAM AND COMPARATIVE EVALUATION OF ORAL AND LOCAL SPIRONOLACTONE EFFICACY IN MANAGEMENT OF HIRSUTISM. KOWSAR MEDICAL JOURNAL[Internet]. 2006;11(3):235-239. Available from: https://sid.ir/paper/32720/en

IEEE: Copy

M. SHOHRATI, SEYED MASOUD DAVOUDI, S.B. SADR, H. JAHANDIDEH, and SH. SABOURI YAZDI, “FORMULATION OF SPIRONOLACTONE CREAM AND COMPARATIVE EVALUATION OF ORAL AND LOCAL SPIRONOLACTONE EFFICACY IN MANAGEMENT OF HIRSUTISM,” KOWSAR MEDICAL JOURNAL, vol. 11, no. 3, pp. 235–239, 2006, [Online]. Available: https://sid.ir/paper/32720/en

Related Journal Papers