OCTODON DEGUS: A STRONG ATTRACTOR FOR ALZHEIMER RESEARCH

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CASTRO FUENTES RAFAEL; SOCAS PEREZ ROSARIO

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Journal: Basic and Clinical Neuroscience Year:2013 | Volume:4 | Issue:1 Page(s): 91-96

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Title

OCTODON DEGUS: A STRONG ATTRACTOR FOR ALZHEIMER RESEARCH

Author(s)

CASTRO FUENTES RAFAEL | SOCAS PEREZ ROSARIO | Issue Writer Certificate

Keywords

ANIMAL MODEL

AGING

OCTODON DEGUS

ALZHEIMER’S DISEASE

Abstract

The most popular ANIMAL MODELs of ALZHEIMER’S DISEASE (AD) are transgenic mice expressing human genes with known mutations which do not represent the most abundant sporadic form of the disease. An increasing number of genetic, vascular and psychosocial data strongly support that the OCTODON DEGUS, a moderate-sized and diurnal precocial rodent, provides a naturalistic model for the study of the early neurodegenerative process associated with sporadic AD. In this minireview we describe and analyze the risk factors that contribute to Alzheimer-like characteristics in the degus, following recent publications, and establish some guidelines for future studies in this model of natural AGING associated with the disease. Given the heterogeneity of current data derived from the diverse transgenic ANIMAL MODELs of AD, now may be the time for the degus to become a strong attractor for academic research labs and companies involved with AD. This may help to understand the mechanisms responsible for the early neurodegenerative process associated with this devastating disease.

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APA: Copy

CASTRO FUENTES, RAFAEL, & SOCAS PEREZ, ROSARIO. (2013). OCTODON DEGUS: A STRONG ATTRACTOR FOR ALZHEIMER RESEARCH. BASIC AND CLINICAL NEUROSCIENCE, 4(1), 91-96. SID. https://sid.ir/paper/327693/en

Vancouver: Copy

CASTRO FUENTES RAFAEL, SOCAS PEREZ ROSARIO. OCTODON DEGUS: A STRONG ATTRACTOR FOR ALZHEIMER RESEARCH. BASIC AND CLINICAL NEUROSCIENCE[Internet]. 2013;4(1):91-96. Available from: https://sid.ir/paper/327693/en

IEEE: Copy

RAFAEL CASTRO FUENTES, and ROSARIO SOCAS PEREZ, “OCTODON DEGUS: A STRONG ATTRACTOR FOR ALZHEIMER RESEARCH,” BASIC AND CLINICAL NEUROSCIENCE, vol. 4, no. 1, pp. 91–96, 2013, [Online]. Available: https://sid.ir/paper/327693/en

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