THE EFFECT OF STIMULATION OF NUCLEUS BASALIS OF MEYNERT ON THE RESPONSE PROPERTIES OF NEURONS OF RAT BARREL CORTEX

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GOSHAD ROU FATEMEH

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Journal: KOWSAR MEDICAL JOURNAL Year:2007 | Volume:12 | Issue:1 Page(s): 1-12

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Title

THE EFFECT OF STIMULATION OF NUCLEUS BASALIS OF MEYNERT ON THE RESPONSE PROPERTIES OF NEURONS OF RAT BARREL CORTEX

Author(s)

GOSHAD ROU FATEMEH | Issue Writer Certificate

Keywords

NUCLEUS BASALIS OF MEYNERT (NBM)Q3

ELECTRICAL STIMULATIONQ3

BARREL CORTEXQ3

SINGLE UNIT RECORDINGQ4

Abstract

Introduction: The aim of this study was to evaluate the effect of stimulation of nucleus basalis of Meynert (NBM) on the response properties of barrel cortical neurons in the rat primary somatosensory cortex.Material and Methods: Extra cellular single-unit recording to computer-controlled displacement of whiskers were obtained in layer V of BARREL CORTEX of Wistar male rats. NBM was electrically stimulated and the response properties of neurons in BARREL CORTEX before and after NBM stimulation were compared.Results: The results showed that NBM ELECTRICAL STIMULATION changes evoked responses in 60.7 % of neurons. The others (39.3%) were not affected. After NBM stimulation the most evident effects were decreasing responses of neurons, which were observed in 76.5% of changed cases. This effect was eliminated within 800 ms. NBM stimulation significantly decreased the response latency, while it did not change the spontaneous activity of neurons.Conclusion: It was concluded that NBM has an important role in regulating the balance of excitation and inhibition in the BARREL CORTEX.

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APA: Copy

GOSHAD ROU, FATEMEH. (2007). THE EFFECT OF STIMULATION OF NUCLEUS BASALIS OF MEYNERT ON THE RESPONSE PROPERTIES OF NEURONS OF RAT BARREL CORTEX. KOWSAR MEDICAL JOURNAL, 12(1), 1-12. SID. https://sid.ir/paper/32845/en

Vancouver: Copy

GOSHAD ROU FATEMEH. THE EFFECT OF STIMULATION OF NUCLEUS BASALIS OF MEYNERT ON THE RESPONSE PROPERTIES OF NEURONS OF RAT BARREL CORTEX. KOWSAR MEDICAL JOURNAL[Internet]. 2007;12(1):1-12. Available from: https://sid.ir/paper/32845/en

IEEE: Copy

FATEMEH GOSHAD ROU, “THE EFFECT OF STIMULATION OF NUCLEUS BASALIS OF MEYNERT ON THE RESPONSE PROPERTIES OF NEURONS OF RAT BARREL CORTEX,” KOWSAR MEDICAL JOURNAL, vol. 12, no. 1, pp. 1–12, 2007, [Online]. Available: https://sid.ir/paper/32845/en

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