KNEE JOINT DEVELOPMENT AND ROLE OF CELL DEATH IN RATS

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MIRSHAFIEI GH.A.; REZAZADEH M.; DASHTNAVARD H.; BAHADORAN H.; KAKA G.; MOFID M.; IMANI H.; SADRAEI S.H.

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Journal: KOWSAR MEDICAL JOURNAL Year:2005 | Volume:10 | Issue:2 Page(s): 89-96

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Title

KNEE JOINT DEVELOPMENT AND ROLE OF CELL DEATH IN RATS

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Keywords

EMBRYO DEVELOPMENTQ3

KNEE JOINTQ3

RATQ3

Abstract

Objective: This study evaluated RAT KNEE JOINT development and the role of cell death in KNEE JOINT cavity formation. Materials and Methods: 108 right RAT limbs of 13-19 days old embryos were selected, fixed, serial sectioned about 5-15 µM thicked after tissue processing and stained with hematoxiline 8- eosin, a1cineblue and phosphatase acid. All slides were studied with light microscopy. Results: Limb buds protruded on the 13th day of development. Separation primary and end parts of the limb bud by two circular constrictions and hemogen, compact cell mesenchyme without vessels condense on the 14th day of development, have able been observed. In the 16 day-old embryo, the primary circular constriction became a 3 layer interzone which has 2 compact cellular layers in the lateral side and one noncompact cellular layers in the middle. More dead cells were seen in the middle zone. In the 17 and 18 day-old embryos, the death of cells were seen in the surface of the femur and tibia bones. Conclusion: The results of this study showed that KNEE JOINT cavity formation after programmed cell death can be observed in interzolle, but no main factor induced this phenomenon were determined.

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APA: Copy

MIRSHAFIEI, GH.A., REZAZADEH, M., DASHTNAVARD, H., BAHADORAN, H., KAKA, G., MOFID, M., IMANI, H., & SADRAEI, S.H.. (2005). KNEE JOINT DEVELOPMENT AND ROLE OF CELL DEATH IN RATS. KOWSAR MEDICAL JOURNAL, 10(2), 89-96. SID. https://sid.ir/paper/32961/en

Vancouver: Copy

MIRSHAFIEI GH.A., REZAZADEH M., DASHTNAVARD H., BAHADORAN H., KAKA G., MOFID M., IMANI H., SADRAEI S.H.. KNEE JOINT DEVELOPMENT AND ROLE OF CELL DEATH IN RATS. KOWSAR MEDICAL JOURNAL[Internet]. 2005;10(2):89-96. Available from: https://sid.ir/paper/32961/en

IEEE: Copy

GH.A. MIRSHAFIEI, M. REZAZADEH, H. DASHTNAVARD, H. BAHADORAN, G. KAKA, M. MOFID, H. IMANI, and S.H. SADRAEI, “KNEE JOINT DEVELOPMENT AND ROLE OF CELL DEATH IN RATS,” KOWSAR MEDICAL JOURNAL, vol. 10, no. 2, pp. 89–96, 2005, [Online]. Available: https://sid.ir/paper/32961/en

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