Hemoglobin-Based Oxygen Carrier for Traumatic Hemorrhagic Shock Treatment in a Jehovah’ s Witness

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Posluszny Joseph A.; Napolitano Lena M.

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Journal Paper

Paper Information

Journal: Archives of Trauma Research Year:2016 | Volume:5 | Issue:2 Page(s): 0-0

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Information Journal Paper

Title

Hemoglobin-Based Oxygen Carrier for Traumatic Hemorrhagic Shock Treatment in a Jehovah’ s Witness

Author(s)

Posluszny Joseph A. | Napolitano Lena M. | Issue Writer Certificate

Keywords

Anemia

Erythropoietin-Stimulating Agents

Hemoglobin-Based Oxygen Carrier

Hepcidin

Iron

Jehovah’s Witness

Abstract

Introduction: Treatment of severe hemorrhagic shock due to acute blood loss from traumatic injuries in a Jehovah’ s witness (JW) trauma patient is very challenging since hemostatic blood product resuscitation is limited by refusal of the transfusion of allogeneic blood products. Case Presentation: We describe a multifaceted approach to the clinical care of a severely anemic JW trauma patient including the early administration of a bovine Hemoglobin-Based Oxygen Carrier (HBOC) as a bridge to resolution of critical Anemia (nadir hemoglobin 3. 9 g/dL). Hemoglobin-Based Oxygen Carrier infusions were used to supplement oxygen delivery until endogenous erythropoiesis could restore adequate red blood cell mass. Subsequent endogenous bone marrow recovery was supported by early administration of high-dose erythropoiesis-stimulating agents and Iron supplementation. Conclusions: Early HBOC administration can be used in the treatment of severe hemorrhagic shock in trauma patients who refuse allogeneic blood.

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APA: Copy

Posluszny, Joseph A., & Napolitano, Lena M.. (2016). Hemoglobin-Based Oxygen Carrier for Traumatic Hemorrhagic Shock Treatment in a Jehovah’ s Witness. ARCHIVES OF TRAUMA RESEARCH, 5(2), 0-0. SID. https://sid.ir/paper/330650/en

Vancouver: Copy

Posluszny Joseph A., Napolitano Lena M.. Hemoglobin-Based Oxygen Carrier for Traumatic Hemorrhagic Shock Treatment in a Jehovah’ s Witness. ARCHIVES OF TRAUMA RESEARCH[Internet]. 2016;5(2):0-0. Available from: https://sid.ir/paper/330650/en

IEEE: Copy

Joseph A. Posluszny, and Lena M. Napolitano, “Hemoglobin-Based Oxygen Carrier for Traumatic Hemorrhagic Shock Treatment in a Jehovah’ s Witness,” ARCHIVES OF TRAUMA RESEARCH, vol. 5, no. 2, pp. 0–0, 2016, [Online]. Available: https://sid.ir/paper/330650/en

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