ASSOCIATION BETWEEN THROMBOPHILIA AND REPEATED ASSISTED REPRODUCTIVE TECHNOLOGY FAILURES

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

HAMDI KOBRA; VAEZI MARYAM; DAGIGAZAR BEHROOZ; MEHRZAD SADAGIANI MAHZAD; FARZADI LAYA; PASHAEI ASL MARYAM

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Advanced Pharmaceutical Bulletin Year:2012 | Volume:2 | Issue:2 Page(s): 233-237

Download Full-Text

View:

278

Download:

123

Cites:

Information Journal Paper

Title

ASSOCIATION BETWEEN THROMBOPHILIA AND REPEATED ASSISTED REPRODUCTIVE TECHNOLOGY FAILURES

Author(s)

Keywords

MUTATION

THROMBOPHILIA

ART

PREGNANCY

Abstract

Purpose: This study was performed to investigate the incidence of thrombophilic gene MUTATIONs in repeated assisted reproductive technology (ART) failures.Methods: The prevalence of mutated genes in the patients with a history of three or more previous ART failures was compared with the patients with a history of successful PREGNANCY following ARTs. The study group included 70 patients, 34 with three or more previously failed ARTs (A) and control group consisted of 36 patients with successful PREGNANCY following ARTs (B). All patients were tested for the presence of mutated thrombophilic genes including factor V Leiden (FVL), Methylenetetrahydrofolate reductase (MTHFR) and Prothrombin (G20210A) using real-time polymerase chain reaction (RT- PCR).Results: MUTATION of FVL gene was detected in 5.9% women of group A (2 of 34) compared with 2.8% women (1 of 36) of control group (P=0.6). MUTATION of MTHFR gene was found in 35.3% (12 cases) as compared with 50% (18 cases) of control (35.3% versus 50%; P=0.23). Regarding Prothrombin, only control group had 5.6% MUTATION (P=0.49). No significant differences were detected in the incidences of FVL, Prothrombin and MTHFR in the study group A compared with the control group B.Conclusion: The obtained results suggest that THROMBOPHILIA does not have a significant effect in ART failures.

Cites

No record.

References

No record.

Cite

APA: Copy

HAMDI, KOBRA, VAEZI, MARYAM, DAGIGAZAR, BEHROOZ, MEHRZAD SADAGIANI, MAHZAD, FARZADI, LAYA, & PASHAEI ASL, MARYAM. (2012). ASSOCIATION BETWEEN THROMBOPHILIA AND REPEATED ASSISTED REPRODUCTIVE TECHNOLOGY FAILURES. ADVANCED PHARMACEUTICAL BULLETIN, 2(2), 233-237. SID. https://sid.ir/paper/331655/en

Vancouver: Copy

HAMDI KOBRA, VAEZI MARYAM, DAGIGAZAR BEHROOZ, MEHRZAD SADAGIANI MAHZAD, FARZADI LAYA, PASHAEI ASL MARYAM. ASSOCIATION BETWEEN THROMBOPHILIA AND REPEATED ASSISTED REPRODUCTIVE TECHNOLOGY FAILURES. ADVANCED PHARMACEUTICAL BULLETIN[Internet]. 2012;2(2):233-237. Available from: https://sid.ir/paper/331655/en

IEEE: Copy

KOBRA HAMDI, MARYAM VAEZI, BEHROOZ DAGIGAZAR, MAHZAD MEHRZAD SADAGIANI, LAYA FARZADI, and MARYAM PASHAEI ASL, “ASSOCIATION BETWEEN THROMBOPHILIA AND REPEATED ASSISTED REPRODUCTIVE TECHNOLOGY FAILURES,” ADVANCED PHARMACEUTICAL BULLETIN, vol. 2, no. 2, pp. 233–237, 2012, [Online]. Available: https://sid.ir/paper/331655/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops