MESENCHYMAL STEM CELL-DERIVED EXOSOMES: NEW OPPORTUNITY IN CELL- FREE THERAPY (EDITORIAL)

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PASHOUTAN SARVAR DAVOD; SHAMSASENJAN KARIM; AKBARZADEHLALEH PARVIN

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Journal Paper

Paper Information

Journal: Advanced Pharmaceutical Bulletin Year:2016 | Volume:6 | Issue:3 Page(s): 293-299

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Information Journal Paper

Title

MESENCHYMAL STEM CELL-DERIVED EXOSOMES: NEW OPPORTUNITY IN CELL- FREE THERAPY (EDITORIAL)

Author(s)

PASHOUTAN SARVAR DAVOD | SHAMSASENJAN KARIM | AKBARZADEHLALEH PARVIN | Issue Writer Certificate

Keywords

MESENCHYMAL STEM CELLS

EXOSOMES

REGENERATIVE MEDICINE

Abstract

Mesenchymal stromal/stem cells (MSCs) are involved in tissue homeostasis through direct cell-to-cell interaction, as well as secretion of soluble factors. EXOSOMES are the sort of soluble biological mediators that obtained from MSCs cultured media in vitro. MSC-derived EXOSOMES (MSC-DEs) which produced under physiological or pathological conditions are central mediators of intercellular communications by conveying proteins, lipids, mRNAs, siRNA, ribosomal RNAs and miRNAs to the neighbor or distant cells. MSC-DEs have been tested in various disease models, and the results have revealed that their functions are similar to those of MSCs. They have the supportive functions in organisms such as repairing tissue damages, suppressing inflammatory responses, and modulating the immune system. MSC-DEs are of great interest in the scope of REGENERATIVE MEDICINE because of their unique capacity to the regeneration of the damaged tissues, and the present paper aims to introduce MSC-DEs as a novel hope in cell-free therapy.

Cites

EFFECTS OF MESENCHYMAL STEM CELL DERIVATIVES ON HEMATOPOIESIS AND HEMATOPOIETIC STEM CELLS

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APA: Copy

PASHOUTAN SARVAR, DAVOD, SHAMSASENJAN, KARIM, & AKBARZADEHLALEH, PARVIN. (2016). MESENCHYMAL STEM CELL-DERIVED EXOSOMES: NEW OPPORTUNITY IN CELL- FREE THERAPY (EDITORIAL). ADVANCED PHARMACEUTICAL BULLETIN, 6(3), 293-299. SID. https://sid.ir/paper/331818/en

Vancouver: Copy

PASHOUTAN SARVAR DAVOD, SHAMSASENJAN KARIM, AKBARZADEHLALEH PARVIN. MESENCHYMAL STEM CELL-DERIVED EXOSOMES: NEW OPPORTUNITY IN CELL- FREE THERAPY (EDITORIAL). ADVANCED PHARMACEUTICAL BULLETIN[Internet]. 2016;6(3):293-299. Available from: https://sid.ir/paper/331818/en

IEEE: Copy

DAVOD PASHOUTAN SARVAR, KARIM SHAMSASENJAN, and PARVIN AKBARZADEHLALEH, “MESENCHYMAL STEM CELL-DERIVED EXOSOMES: NEW OPPORTUNITY IN CELL- FREE THERAPY (EDITORIAL),” ADVANCED PHARMACEUTICAL BULLETIN, vol. 6, no. 3, pp. 293–299, 2016, [Online]. Available: https://sid.ir/paper/331818/en

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