EVALUATION OF BETULIN MUTAGENICITY BY SALMONELLA/MICROSOME TEST (SHORT COMMUNICATION)

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

YOSHIDA EDSON HIDEAKI; TRIBUIANI NATALIA; SABADIM GIOVANA; NETO MORENO DEBORA ANTUNES; APARECIDA VARANDA ELIANA; OSHIMA FRANCO YOKO

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Advanced Pharmaceutical Bulletin Year:2016 | Volume:6 | Issue:3 Page(s): 443-447

Download Full-Text

View:

462

Download:

151

Cites:

Information Journal Paper

Title

EVALUATION OF BETULIN MUTAGENICITY BY SALMONELLA/MICROSOME TEST (SHORT COMMUNICATION)

Author(s)

Keywords

AMES TEST

BETULIN

SALMONELLA MUTAGENICITY

TRITERPENOID

Abstract

Purpose: BETULIN is a pentacyclic triterpene found in the outer barks of innumerous plants. This secondary metabolite is easily isolated from plants with the major interest in converting it to BETULINic acid, which pharmacological properties were much more exploited than BETULIN. But, investments in the own BETULIN have been grown since no chemical step is necessary. In this study we focused the precursor BETULIN in order to evaluate its mutagenicity by Salmonella/microsome assay (AMES TEST).Methods: The AMES TEST was carried out using a commercial BETULIN exposed to Salmonella typhimurium strains TA98, TA100, TA102, and TA97a, in experiments with (+S9) and without (-S9) metabolic activation.Results: BETULIN was unable to increase the number of revertants (+S9 and -S9 metabolic activation) showing the absence of any mutagenic effect by AMES TEST.Conclusion: This study allowed attribute safety to BETULIN being important for exploiting its pharmacological uses.

Cites

No record.

References

No record.

Cite

APA: Copy

YOSHIDA, EDSON HIDEAKI, TRIBUIANI, NATALIA, SABADIM, GIOVANA, NETO MORENO, DEBORA ANTUNES, APARECIDA VARANDA, ELIANA, & OSHIMA FRANCO, YOKO. (2016). EVALUATION OF BETULIN MUTAGENICITY BY SALMONELLA/MICROSOME TEST (SHORT COMMUNICATION). ADVANCED PHARMACEUTICAL BULLETIN, 6(3), 443-447. SID. https://sid.ir/paper/331822/en

Vancouver: Copy

YOSHIDA EDSON HIDEAKI, TRIBUIANI NATALIA, SABADIM GIOVANA, NETO MORENO DEBORA ANTUNES, APARECIDA VARANDA ELIANA, OSHIMA FRANCO YOKO. EVALUATION OF BETULIN MUTAGENICITY BY SALMONELLA/MICROSOME TEST (SHORT COMMUNICATION). ADVANCED PHARMACEUTICAL BULLETIN[Internet]. 2016;6(3):443-447. Available from: https://sid.ir/paper/331822/en

IEEE: Copy

EDSON HIDEAKI YOSHIDA, NATALIA TRIBUIANI, GIOVANA SABADIM, DEBORA ANTUNES NETO MORENO, ELIANA APARECIDA VARANDA, and YOKO OSHIMA FRANCO, “EVALUATION OF BETULIN MUTAGENICITY BY SALMONELLA/MICROSOME TEST (SHORT COMMUNICATION),” ADVANCED PHARMACEUTICAL BULLETIN, vol. 6, no. 3, pp. 443–447, 2016, [Online]. Available: https://sid.ir/paper/331822/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops