OVERVIEW OF ALBUMIN AND ITS PURIFICATION METHODS (MINI REVIEW)

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Raoufinia Ramin; MOTA ALI; Keyhanvar Neda; SAFARI FATEMEH; Shamekhi Sara; ABDOLALIZADEH JALAL

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Journal: Advanced Pharmaceutical Bulletin Year:2016 | Volume:6 | Issue:4 Page(s): 495-507

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Title

OVERVIEW OF ALBUMIN AND ITS PURIFICATION METHODS (MINI REVIEW)

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Keywords

HUMAN SERUM ALBUMIN

PURIFICATION

CHROMATOGRAPHY

IMMUNOAFFINITY

Abstract

As the most frequent plasma protein, albumin constitutes more than 50% of the serum proteins in healthy individuals. It has a key role in oncotic pressure maintenance and it is known as a versatile protein carrier for transportation of various endogenous and exogenous ligands. Reduced amounts of albumin in the body will lead to different kinds of diseases such as hypovolemia and hypoproteinemia. It also has various indications in shocks, burns, cardiopulmonary bypass, acute liver failure and etc. Further applications in research consist of cell culture supplement, drug delivery carrier and protein/drug stabilizer. So, the demand for albumin increased annually worldwide. Due to different applications of albumin, many efforts have been accomplished to achieve albumin during a long period of time. In this review, an overview of serum albumin and different PURIFICATION methods are summarized.

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APA: Copy

Raoufinia, Ramin, MOTA, ALI, Keyhanvar, Neda, SAFARI, FATEMEH, Shamekhi, Sara, & ABDOLALIZADEH, JALAL. (2016). OVERVIEW OF ALBUMIN AND ITS PURIFICATION METHODS (MINI REVIEW). ADVANCED PHARMACEUTICAL BULLETIN, 6(4), 495-507. SID. https://sid.ir/paper/331848/en

Vancouver: Copy

Raoufinia Ramin, MOTA ALI, Keyhanvar Neda, SAFARI FATEMEH, Shamekhi Sara, ABDOLALIZADEH JALAL. OVERVIEW OF ALBUMIN AND ITS PURIFICATION METHODS (MINI REVIEW). ADVANCED PHARMACEUTICAL BULLETIN[Internet]. 2016;6(4):495-507. Available from: https://sid.ir/paper/331848/en

IEEE: Copy

Ramin Raoufinia, ALI MOTA, Neda Keyhanvar, FATEMEH SAFARI, Sara Shamekhi, and JALAL ABDOLALIZADEH, “OVERVIEW OF ALBUMIN AND ITS PURIFICATION METHODS (MINI REVIEW),” ADVANCED PHARMACEUTICAL BULLETIN, vol. 6, no. 4, pp. 495–507, 2016, [Online]. Available: https://sid.ir/paper/331848/en

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