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Information Journal Paper

Title

Novel Combination of Silver Nanoparticles and Carbon Nanotubes for Plasmonic Photo Thermal Therapy in Melanoma Cancer Model

Pages

  49-55

Abstract

 Purpose: Plasmonic photo thermal therapy (PPTT) is a therapeutic method in which the photon energy is rapidly transformed into heat via a series of radiative and non-radiative phenomena to ablate cancer. Plasmonic NPs, such as silver NPs (Ag NPs), have considerable properties in optical absorbance. Furthermore, good thermal conductivity and cell penetration ability of Carbon nanotubes (CNTs) could improve the efficacy of Ag NPs for PPTT. Decoration of the multi-walled Carbon nanotubes (MWCNTs) with silver has been developed to enhance thermal conductivity of the MWCNT particles. Methods: The Ag NPs were decorated on the CNTs and the ability of these particles (CNT/Ag NPs) in reduction of melanoma tumor size after PTT was evaluated experimentally. For comparison, the PTT of Silver nanorods (Ag NRs) and CNTs were investigated. The melanoma tumor was induced by injection of B16/F10 cell line to the inbred mice. Different NPs were injected into the tumors and then irradiated via Laser diode (λ =670 nm, P=500 mW, and I= 3. 5 W/cm2) at scheduled time. Results: Monitoring of tumor sizes showed that integration of CNTs with silver could enhance the optical absorption of CNTs and improve tumor destruction in PPTT technique. Conclusion: The CNT/Ag NPs could act as a potent agent in PPTT method in curing solid tumors.

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    APA: Copy

    Behnam, Mohammad Ali, EMAMI, FARZIN, SOBHANI, ZAHRA, KOOHI HOSSEINABADI, OMID, DEHGHANIAN, AMIR REZA, ZEBARJAD, SEYED MOJTABA, Moghim, Mohammad Hadi, & ORYAN, AHMAD. (2018). Novel Combination of Silver Nanoparticles and Carbon Nanotubes for Plasmonic Photo Thermal Therapy in Melanoma Cancer Model. ADVANCED PHARMACEUTICAL BULLETIN, 8(1), 49-55. SID. https://sid.ir/paper/331904/en

    Vancouver: Copy

    Behnam Mohammad Ali, EMAMI FARZIN, SOBHANI ZAHRA, KOOHI HOSSEINABADI OMID, DEHGHANIAN AMIR REZA, ZEBARJAD SEYED MOJTABA, Moghim Mohammad Hadi, ORYAN AHMAD. Novel Combination of Silver Nanoparticles and Carbon Nanotubes for Plasmonic Photo Thermal Therapy in Melanoma Cancer Model. ADVANCED PHARMACEUTICAL BULLETIN[Internet]. 2018;8(1):49-55. Available from: https://sid.ir/paper/331904/en

    IEEE: Copy

    Mohammad Ali Behnam, FARZIN EMAMI, ZAHRA SOBHANI, OMID KOOHI HOSSEINABADI, AMIR REZA DEHGHANIAN, SEYED MOJTABA ZEBARJAD, Mohammad Hadi Moghim, and AHMAD ORYAN, “Novel Combination of Silver Nanoparticles and Carbon Nanotubes for Plasmonic Photo Thermal Therapy in Melanoma Cancer Model,” ADVANCED PHARMACEUTICAL BULLETIN, vol. 8, no. 1, pp. 49–55, 2018, [Online]. Available: https://sid.ir/paper/331904/en

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