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Information Journal Paper

Title

The Association Analysis of Vascular Endothelial Growth Factor-2549 Insertion/ Deletion Variant and Endometriosis Risk

Pages

  1-6

Abstract

 Endometriosis is a debilitating disorder, defined as the presence of endometrial gland and stroma outside of the uterus. It may affect angiogenesis and vascular endothelial growth factor (VEGF) is one of the angiogenic factors that plays an important role in both physiological and pathological angiogenesis. The present study aimed to evaluate the association of VEGF-2549 insertion/deletion (I/D) polymorphism with Endometriosis. This casecontrol study enrolled 244 (100 cases and 144 controls) women who were admitted for laparoscopy or laparotomy for gynecological procedures. Genomic DNA was separated from peripheral blood leukocytes and polymerase chain reaction (PCR) amplification was performed for genotyping of the VEGF gene Insertion/Deletion (I/D) polymorphism. The frequency of the II, ID, and DD genotype was 14%, 52% and 34% in patients versus 18. 8%, 47. 8% and 34% in controls. The results did not provide any evidence supporting the Endometriosis risk related to the VEGF polymorphism in a group of Iranian women population.

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    APA: Copy

    Sarhangi, Negar, MOHSENI, SHAHRZAD, AMINIMOGHADDAM, SOHEILA, HOSSEIN RASHIDI, BATOOL, HAGHOLLAHI, FEDYEH, QORBANI, MOSTAFA, MOHAMMAD AMOLI, MAHSA, & Shahrabi Farahani, Maryam. (2019). The Association Analysis of Vascular Endothelial Growth Factor-2549 Insertion/ Deletion Variant and Endometriosis Risk. INTERNATIONAL JOURNAL OF MOLECULAR AND CELLULAR MEDICINE, 8(supp), 1-6. SID. https://sid.ir/paper/332259/en

    Vancouver: Copy

    Sarhangi Negar, MOHSENI SHAHRZAD, AMINIMOGHADDAM SOHEILA, HOSSEIN RASHIDI BATOOL, HAGHOLLAHI FEDYEH, QORBANI MOSTAFA, MOHAMMAD AMOLI MAHSA, Shahrabi Farahani Maryam. The Association Analysis of Vascular Endothelial Growth Factor-2549 Insertion/ Deletion Variant and Endometriosis Risk. INTERNATIONAL JOURNAL OF MOLECULAR AND CELLULAR MEDICINE[Internet]. 2019;8(supp):1-6. Available from: https://sid.ir/paper/332259/en

    IEEE: Copy

    Negar Sarhangi, SHAHRZAD MOHSENI, SOHEILA AMINIMOGHADDAM, BATOOL HOSSEIN RASHIDI, FEDYEH HAGHOLLAHI, MOSTAFA QORBANI, MAHSA MOHAMMAD AMOLI, and Maryam Shahrabi Farahani, “The Association Analysis of Vascular Endothelial Growth Factor-2549 Insertion/ Deletion Variant and Endometriosis Risk,” INTERNATIONAL JOURNAL OF MOLECULAR AND CELLULAR MEDICINE, vol. 8, no. supp, pp. 1–6, 2019, [Online]. Available: https://sid.ir/paper/332259/en

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