OROPHARYNGEAL CANDIDIASIS AND RESISTANCE TO ANTIFUNGAL DRUGS IN PATIENTS RECEIVING RADIATION FOR HEAD AND NECK CANCER

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

RAD MARYAM; AYATOLLAHI MOUSAVI SEYYED AMIN; KAKOEI SHAHLA; BAHADOR MARYAM; BORNA ROYA; LASHKARIZADEH NAZILA

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: JOURNAL OF ORAL HEALTH AND ORAL EPIDEMIOLOGY Year:2012 | Volume:1 | Issue:1 Page(s): 36-40

Download Full-Text

View:

341

Download:

157

Cites:

Information Journal Paper

Title

OROPHARYNGEAL CANDIDIASIS AND RESISTANCE TO ANTIFUNGAL DRUGS IN PATIENTS RECEIVING RADIATION FOR HEAD AND NECK CANCER

Author(s)

Keywords

OROPHARYNGEAL CANDIDIASIS

RADIATION

COLONIZATION

ANTIFUNGAL DRUGS

CANCER

Abstract

BACKGROUND: OROPHARYNGEAL CANDIDIASIS is a common infection in patient receiving radiotherapy for head and neck CANCER. Accurate and rapid identification of candida species is very important in clinical laboratory, because the incidence of candidiasis continues to rise after radiotherapy. The genus Candida has about 154 species that show different level of resistance to ANTIFUNGAL DRUGS and have high degree of phenotypic similarity. The aim of this study was to investigate oral yeast COLONIZATION and infection and resistance to ANTIFUNGAL DRUGS in these patients.METHODS: Thirty patients receiving a 6-week course of RADIATION therapy for treatment of head and neck CANCER at the Oncology Unit in Shafa Hospital, in 2008, were enrolled in the study. Specimens from patients were cultured weekly for Candida. All isolates were plated on CHROM agar and RPMI-based medium. They were subcultured and submitted for antifungal susceptibility testing (nystatin, fluconazole, clotrimazole and ketoconazole) and molecular typing.RESULTS: Infection (clinical and microbiological evidence) occurred in 50% of the patients and Candida COLONIZATION (only microbiological evidence) occurred in 70% of subjects in the first week. Candida albicans alone was isolated in 94.9% of patient visits with positive cultures. Candida tropicalis was isolated from 5.1% of patient visits with positive cultures. All isolates were susceptible to nystatin, but did not respond to the other ANTIFUNGAL DRUGSCONCLUSIONS: The irradiation-induced changes of the intraoral environment such as xerostomia lead to increased intraoral COLONIZATION by Candida species. All yeast isolates were susceptible to nystatin. Thus prophylactic therapy with nystatin should be considered for these patients.

Cites

No record.

References

No record.

Cite

APA: Copy

RAD, MARYAM, AYATOLLAHI MOUSAVI, SEYYED AMIN, KAKOEI, SHAHLA, BAHADOR, MARYAM, BORNA, ROYA, & LASHKARIZADEH, NAZILA. (2012). OROPHARYNGEAL CANDIDIASIS AND RESISTANCE TO ANTIFUNGAL DRUGS IN PATIENTS RECEIVING RADIATION FOR HEAD AND NECK CANCER. JOURNAL OF ORAL HEALTH AND ORAL EPIDEMIOLOGY, 1(1), 36-40. SID. https://sid.ir/paper/333680/en

Vancouver: Copy

RAD MARYAM, AYATOLLAHI MOUSAVI SEYYED AMIN, KAKOEI SHAHLA, BAHADOR MARYAM, BORNA ROYA, LASHKARIZADEH NAZILA. OROPHARYNGEAL CANDIDIASIS AND RESISTANCE TO ANTIFUNGAL DRUGS IN PATIENTS RECEIVING RADIATION FOR HEAD AND NECK CANCER. JOURNAL OF ORAL HEALTH AND ORAL EPIDEMIOLOGY[Internet]. 2012;1(1):36-40. Available from: https://sid.ir/paper/333680/en

IEEE: Copy

MARYAM RAD, SEYYED AMIN AYATOLLAHI MOUSAVI, SHAHLA KAKOEI, MARYAM BAHADOR, ROYA BORNA, and NAZILA LASHKARIZADEH, “OROPHARYNGEAL CANDIDIASIS AND RESISTANCE TO ANTIFUNGAL DRUGS IN PATIENTS RECEIVING RADIATION FOR HEAD AND NECK CANCER,” JOURNAL OF ORAL HEALTH AND ORAL EPIDEMIOLOGY, vol. 1, no. 1, pp. 36–40, 2012, [Online]. Available: https://sid.ir/paper/333680/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops