Hyperthermia and Rigidity Following Overdose of an Unknown Drug; A Case Report and Literature Review

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Dean Paccagnella Rose; Creed Matthew; Kakollu Mahendra; Gopala Pillai Suresh Kumar

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Journal Paper

Paper Information

Journal: Bulletin of Emergency And Trauma Year:2018 | Volume:6 | Issue:3 Page(s): 249-252

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Information Journal Paper

Title

Hyperthermia and Rigidity Following Overdose of an Unknown Drug; A Case Report and Literature Review

Author(s)

Dean Paccagnella Rose | Creed Matthew | Kakollu Mahendra | Gopala Pillai Suresh Kumar | Issue Writer Certificate

Keywords

Serotonin syndrome

Overdose

Hyperthermia

Hypertonicity.

Abstract

Drug induced Hyperthermia is a rare presentation which can rapidly lead to gross metabolic abnormality and death. These presentations are further complicated by the wide range of potentially causative agents. We present a case of rigidity and Hyperthermia, following Overdose of an initially unknown substance leading to challenging management decisions in the Emergency Department. This case was later identified as Serotonin syndrome. The patient presented with trismus which was managed with rapid sequence induction of anaesthesia to allow airway protection. On extubation a significant degree of laryngeal oedema complicated weaning, a possible complication of Serotonin syndrome not previously described in the literature. We discuss the pathophysiology of Serotonin syndrome, important differentials and practical considerations in managing Hypertonicity.of unknown origin in a young person.

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References

Controversies in Serotonin Syndrome Diagnosis and Management: A Review

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APA: Copy

Dean Paccagnella, Rose, Creed, Matthew, Kakollu, Mahendra, & Gopala Pillai, Suresh Kumar. (2018). Hyperthermia and Rigidity Following Overdose of an Unknown Drug; A Case Report and Literature Review. BULLETIN OF EMERGENCY AND TRAUMA BEAT, 6(3), 249-252. SID. https://sid.ir/paper/335127/en

Vancouver: Copy

Dean Paccagnella Rose, Creed Matthew, Kakollu Mahendra, Gopala Pillai Suresh Kumar. Hyperthermia and Rigidity Following Overdose of an Unknown Drug; A Case Report and Literature Review. BULLETIN OF EMERGENCY AND TRAUMA BEAT[Internet]. 2018;6(3):249-252. Available from: https://sid.ir/paper/335127/en

IEEE: Copy

Rose Dean Paccagnella, Matthew Creed, Mahendra Kakollu, and Suresh Kumar Gopala Pillai, “Hyperthermia and Rigidity Following Overdose of an Unknown Drug; A Case Report and Literature Review,” BULLETIN OF EMERGENCY AND TRAUMA BEAT, vol. 6, no. 3, pp. 249–252, 2018, [Online]. Available: https://sid.ir/paper/335127/en

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