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Information Journal Paper

Title

Effects of Chitosan/Nano Selenium Biofilm on Infected Wound Healing in Rats; An Experimental Study

Pages

  284-291

Abstract

 Objective: The present study was aimed at assessment of effect of application of Chitosan/Nano Selenium Biofilm on Infected wound healing in Rats Methods: Sixty-eight male Wistar Rats were randomized into four groups of 17 animals each. In group I (Normal) the wounds were created with no infection. In group II (MRSA), the wounds were infected with methicillin resistant Staphylococcus aureus (MRSA). In group III (MRSA/CHIT), animals with Infected wounds were dressed with chitosan Biofilm only. In group IV (MRSA/CHIT/NS), animals with Infected wounds were dressed with Chitosan/Nano Selenium Biofilm. Results: There were significant differences in comparisons of group IV and other groups, particularly in terms of cellular infiltRation and neovascularization. During the study period, scores for neovascularization was significantly higher in group IV Rats than other groups (p<0. 05). Polymorphonuclear (PMN) and mononuclear (MNC) cell count and fibroblast cell prolifeRation in group IV were significantly higher than those of other experimental groups (p<0. 05) Conclusion: Chitosan/Nano Selenium Biofilm resulted in significant improvement in histopathological indices in full thickness Infected wound healing.

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    Cite

    APA: Copy

    ABBASZADEH, ABOLFAZL, Tehmasebi Foolad, Akram, RAJABZADEH, ASGHAR, Beigi Brojeni, Nasim, & ZAREI, LEILA. (2019). Effects of Chitosan/Nano Selenium Biofilm on Infected Wound Healing in Rats; An Experimental Study. BULLETIN OF EMERGENCY AND TRAUMA BEAT, 7(3), 284-291. SID. https://sid.ir/paper/335180/en

    Vancouver: Copy

    ABBASZADEH ABOLFAZL, Tehmasebi Foolad Akram, RAJABZADEH ASGHAR, Beigi Brojeni Nasim, ZAREI LEILA. Effects of Chitosan/Nano Selenium Biofilm on Infected Wound Healing in Rats; An Experimental Study. BULLETIN OF EMERGENCY AND TRAUMA BEAT[Internet]. 2019;7(3):284-291. Available from: https://sid.ir/paper/335180/en

    IEEE: Copy

    ABOLFAZL ABBASZADEH, Akram Tehmasebi Foolad, ASGHAR RAJABZADEH, Nasim Beigi Brojeni, and LEILA ZAREI, “Effects of Chitosan/Nano Selenium Biofilm on Infected Wound Healing in Rats; An Experimental Study,” BULLETIN OF EMERGENCY AND TRAUMA BEAT, vol. 7, no. 3, pp. 284–291, 2019, [Online]. Available: https://sid.ir/paper/335180/en

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