TOXIDROME BASED APPROACH TO COMMON POISONINGS

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MEGARBANE BRUNO

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Journal Paper

Paper Information

Journal: ASIA PACIFIC JOURNAL OF MEDICAL TOXICOLOGY Year:2014 | Volume:3 | Issue:1 Page(s): 2-12

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Information Journal Paper

Title

TOXIDROME BASED APPROACH TO COMMON POISONINGS

Author(s)

MEGARBANE BRUNO | Issue Writer Certificate

Keywords

ANTICHOLINERGIC SYNDROME

POISONING

SEROTONIN SYNDROME

SUBSTANCE WITHDRAWAL SYNDROME

TOXIDROME

Abstract

Poisoning remains a major cause of hospital admission into the emergency department and intensive care unit. Proper diagnosis is the cornerstone for optimal management of poisoned patients. Since the definitive analytical confirmation of the nature of the toxicant involved in the poisoning cannot be rapidly obtained in the majority of healthcare facilities, diagnosis relies on the medical history and the rigorous clinical examination of the patients well as results of the routine biological tests and the electrocardiogram. Identification of the toxidromes addresses not only the correct diagnosis but also rules out other differential diagnoses. Despite no definitive predictive value, this clinical approach facilitates making decision on empirical treatments and emergent antidotes. Pharmacodynamic tests using specific antidotes including naloxone for opioids and flumazenil for benzodiazepines and its analogues are also helpful to assess the final diagnosis in comatose patients. The objective of this article is to review the toxidromebased approach to common poisonings before toxicological analysis enables the confirmation of the initially suspected toxic etiology.

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APA: Copy

MEGARBANE, BRUNO. (2014). TOXIDROME BASED APPROACH TO COMMON POISONINGS. ASIA PACIFIC JOURNAL OF MEDICAL TOXICOLOGY (APJMT), 3(1), 2-12. SID. https://sid.ir/paper/336355/en

Vancouver: Copy

MEGARBANE BRUNO. TOXIDROME BASED APPROACH TO COMMON POISONINGS. ASIA PACIFIC JOURNAL OF MEDICAL TOXICOLOGY (APJMT)[Internet]. 2014;3(1):2-12. Available from: https://sid.ir/paper/336355/en

IEEE: Copy

BRUNO MEGARBANE, “TOXIDROME BASED APPROACH TO COMMON POISONINGS,” ASIA PACIFIC JOURNAL OF MEDICAL TOXICOLOGY (APJMT), vol. 3, no. 1, pp. 2–12, 2014, [Online]. Available: https://sid.ir/paper/336355/en

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