مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

video

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

sound

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Version

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View:

155
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download:

102
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Cites:

Information Journal Paper

Title

The Efficacy of Aminophylline on Raising Consciousness in Benzodiazepines-Intoxicated Patients

Pages

  17-19

Abstract

 Background: Loss of Consciousness and respiratory failure are the most important medical problems in acute Benzodiazepines (BZDs) Toxicity. The possibility of respiratory apnea increases in intentional cases and also in the presence of underlying cardiopulmonary diseases. The inhibitory effect of Aminophylline on adenosine receptor may be the cause of recovery of Consciousness in patients intoxicated by BZDs. The effect of Aminophylline as an agonist of cAMP (cyclic adenosine monophosphate), on reversal of inhibitory effects of BZDs (Benzodiazepines) on the brain and increasing the level of Consciousness is the main question. Method: we reviewed literature sources on topic of Aminophylline and Consciousness. 29 articles were compiled from prestigious scientific databases such as PubMed, Scopus and Elsevier, from 1983 to 2017. Results: This review showed that intravenous Aminophylline can lead to clinical improvement of both Consciousness and respiration via antagonizing sedation that induced by BZDs. Although administration of flumazenil is still the first choice for apnea related to BZDs overdose and it is also more potent than Aminophylline on reversing sedation, Aminophylline can be substituted when flumazenil is not available or when it has contraindication such as in epileptic patients and in overdoses with drugs capable of causing convulsion. Also, Aminophylline is useful in those BZD-intoxicated patients with coincident underlying COPD and asthma. Conclusion: intravenous Aminophylline could decrease the sedative effects of BZDs and also speed up the recovery of Consciousness in patients under sedative effects of BZDs.

Cites

  • No record.

    • References

    Cite

    APA: Copy

    Aghabiklooei, Abbas. (2018). The Efficacy of Aminophylline on Raising Consciousness in Benzodiazepines-Intoxicated Patients. ASIA PACIFIC JOURNAL OF MEDICAL TOXICOLOGY (APJMT), 7(1), 17-19. SID. https://sid.ir/paper/336414/en

    Vancouver: Copy

    Aghabiklooei Abbas. The Efficacy of Aminophylline on Raising Consciousness in Benzodiazepines-Intoxicated Patients. ASIA PACIFIC JOURNAL OF MEDICAL TOXICOLOGY (APJMT)[Internet]. 2018;7(1):17-19. Available from: https://sid.ir/paper/336414/en

    IEEE: Copy

    Abbas Aghabiklooei, “The Efficacy of Aminophylline on Raising Consciousness in Benzodiazepines-Intoxicated Patients,” ASIA PACIFIC JOURNAL OF MEDICAL TOXICOLOGY (APJMT), vol. 7, no. 1, pp. 17–19, 2018, [Online]. Available: https://sid.ir/paper/336414/en

    Related Journal Papers

  • No record.

    • Related Seminar Papers

  • No record.

    • Related Plans

  • No record.

    • Recommended Workshops






    Move to top
    telegram sharing button
    whatsapp sharing button
    linkedin sharing button
    twitter sharing button
    email sharing button
    email sharing button
    email sharing button
    sharethis sharing button