THE STRUCTURE AND MODE OF ACTION OF THE DINOFLAGELLATE TOXINS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

NAJAFI A.; NABIPOUR I.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download Full-Text

Persian Verion

View:

2,454

Download:

Cites:

Information Journal Paper

Title

THE STRUCTURE AND MODE OF ACTION OF THE DINOFLAGELLATE TOXINS

Author(s)

NAJAFI A. | NABIPOUR I. | Issue Writer Certificate

Keywords

DINOFLAGELLATESQ1

MARINE TOXINSQ1

MARINE TOXICITYQ1

MARINE TOXINOLOGYQ1

Abstract

Background: DINOFLAGELLATES are the major causative agents of harmful algal blooms. In different studies, it has been shown that many dinoflagellate species produce various natural toxins. Saxitoxin, brevetoxin, yessotoxin, etc can be considered as the most important neurotoxins. The most important dinoflagellate toxins structures, their origin, structure and mechanisms of action were evaluated in a systematic review.Materials & Methods: Marine DINOFLAGELLATES, MARINE TOXINS, and their mechanisms of action and structure were keywords for a comprehensive search in online databases including Pubmed, Science Direct, Google Scholar and Scirus. A total of 95 papers were evaluated, however, by omitting similar reports, 68 papers were included in the study.Results: DINOFLAGELLATES toxins are usually polycyclic ether and polyketaide compounds that have distinct mechanisms of action including alteration in different ion channels and/or pumps at cell membrane, effect on the normal functioning of neuronal and other excitable tissues, inhibition of serine/threonine phosphoprotein phosphatases, disrupting major mechanisms of controlling cellular functions, and alteration in cellular cytoskeleton. However, the precise mechanisms of action of few toxins are not determined yet.Conclusion: The clarification of the dinoflagellate toxins structures and their mechanisms of action may be helpful for novel drug design, therapeutic measures and to overcome against MARINE TOXICITY.

Cites

No record.

References

No record.

Cite

APA: Copy

NAJAFI, A., & NABIPOUR, I.. (2016). THE STRUCTURE AND MODE OF ACTION OF THE DINOFLAGELLATE TOXINS. IRANIAN SOUTH MEDICAL JOURNAL (ISMJ), 19(3 ), 457-481. SID. https://sid.ir/paper/33690/en

Vancouver: Copy

NAJAFI A., NABIPOUR I.. THE STRUCTURE AND MODE OF ACTION OF THE DINOFLAGELLATE TOXINS. IRANIAN SOUTH MEDICAL JOURNAL (ISMJ)[Internet]. 2016;19(3 ):457-481. Available from: https://sid.ir/paper/33690/en

IEEE: Copy

A. NAJAFI, and I. NABIPOUR, “THE STRUCTURE AND MODE OF ACTION OF THE DINOFLAGELLATE TOXINS,” IRANIAN SOUTH MEDICAL JOURNAL (ISMJ), vol. 19, no. 3 , pp. 457–481, 2016, [Online]. Available: https://sid.ir/paper/33690/en

Related Journal Papers