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Title

ATRIAL AND VENTRICULAR ELECTROCARDIOGRAPHIC DROMOTROPIC DISTURBANCES IN DOWN SYNDROME PATIENTS WITH STRUCTURALLY NORMAL HEART: A CROSS-SECTIONAL STUDY

Pages

  7345-7351

Abstract

 Background: We designed a cross-sectional study to determine electrocardiographic disorders in DOWN SYNDROME patients with congenitally normal hearts in a bid to predict fatal cardiac arrhythmia in the future.Materials and Methods: We investigated 60 CHILDREN with DS without congenital abnormal hearts. Sixty healthy juveniles were also included in the study as a control group. Physical examination, electrocardiography, and echocardiography were performed in all subjects. Corrected QT interval (QTc) was measured according to Bazett’s formula.Results: Patients with DS consisted of 32 males (53.33%), and 28 females (46.66%), aged 6–13 (9.21 ± 6.24) years old. Healthy subjects comprised 31 males (51.66%), and 29 females (48.33%) with a mean age of 9.15 ± 5.01. The two groups were significantly different in terms of heart rate (P=0.006), maximum P-wave duration (P=0.001), and P-wave dispersion (PWd, P=0.0001). There was no statistically significant difference regarding minimum P-wave duration (P=0.176). The patients with DS had a greater maximum QTc interval, QT dispersion, and corrected QT interval dispersion (QTc-d) than the healthy control subjects (P=0.001). However, there was no difference in maximum QT interval and minimum QTc interval between the two groups (P=0.67 and P=0.553, respectively). A positive correlation was found between age, heart rate, and all electrocardiographic variables.Conclusion: All DS patients, even in the absence of concomitant congenital heart disease should be followed up carefully by electrocardiography, looking for increased PWd and QTc-d to detect predisposed cases to arrhythmia.

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    APA: Copy

    GHANDI, YAZDAN, SHARIFI, MEHRZAD, HABIBI, DANIAL, ALINEJAD, SAEED, ARJMAND, ALI, & NIKDEL, SARA. (2018). ATRIAL AND VENTRICULAR ELECTROCARDIOGRAPHIC DROMOTROPIC DISTURBANCES IN DOWN SYNDROME PATIENTS WITH STRUCTURALLY NORMAL HEART: A CROSS-SECTIONAL STUDY. INTERNATIONAL JOURNAL OF PEDIATRICS, 6(3 (51)), 7345-7351. SID. https://sid.ir/paper/337402/en

    Vancouver: Copy

    GHANDI YAZDAN, SHARIFI MEHRZAD, HABIBI DANIAL, ALINEJAD SAEED, ARJMAND ALI, NIKDEL SARA. ATRIAL AND VENTRICULAR ELECTROCARDIOGRAPHIC DROMOTROPIC DISTURBANCES IN DOWN SYNDROME PATIENTS WITH STRUCTURALLY NORMAL HEART: A CROSS-SECTIONAL STUDY. INTERNATIONAL JOURNAL OF PEDIATRICS[Internet]. 2018;6(3 (51)):7345-7351. Available from: https://sid.ir/paper/337402/en

    IEEE: Copy

    YAZDAN GHANDI, MEHRZAD SHARIFI, DANIAL HABIBI, SAEED ALINEJAD, ALI ARJMAND, and SARA NIKDEL, “ATRIAL AND VENTRICULAR ELECTROCARDIOGRAPHIC DROMOTROPIC DISTURBANCES IN DOWN SYNDROME PATIENTS WITH STRUCTURALLY NORMAL HEART: A CROSS-SECTIONAL STUDY,” INTERNATIONAL JOURNAL OF PEDIATRICS, vol. 6, no. 3 (51), pp. 7345–7351, 2018, [Online]. Available: https://sid.ir/paper/337402/en

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