Seroprevalence of Hepatitis B and C Virus Infection in Children with Chronic Kidney Diseases; A Historical Cohort Study

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ATAEI NEAMATOLLAH; HOSSEINI MOSTAFA; YOUSEFIFARD MAHMOUD; ORAII ALIREZA; ATAEI FATEMEH; ABBASI ARASH; RAEESSI NEDA; MOGHTADERI MASTANEH; BAZARGANI BEHNAZ

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Journal: Journal of Pediatric Perspectives Year:2018 | Volume:6 | Issue:1 (49) Page(s): 6911-6917

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Title

Seroprevalence of Hepatitis B and C Virus Infection in Children with Chronic Kidney Diseases; A Historical Cohort Study

Author(s)

Keywords

Child

Hepatitis B

Hepatitis C

Kidney diseases

Prevalence

Risk Factors

Abstract

Background The Prevalence of Hepatitis B and C in Iranian Children with chronic kidney disease is limited. Therefore, the present study intends to assess the Prevalence of Hepatitis B and C in Children with chronic kidney disease (CKD). Materials and Methods: The present study is a historical cohort study which was conducted in a window period of 25 years in Children’ s Medical Center in Tehran, 1991-2016. Data (age, gender, duration of hemodialysis, kidney transplant, and severity of CKD) were extracted from hospital profiles of admitted patients. Infection with Hepatitis B or C viruses was considered as primary outcome. At the end, results were reported as odds ratio (OR) with a confidence interval of 95 per cent (95% CI). Results: Three hundred and fifty five Children (50. 1% boys, mean age of 54. 5± 89. 0 months) were assessed. Hepatitis B and Hepatitis C were detected in 9 (2. 5%) and 5 (1. 4%) Children, respectively. Ten Children had either Hepatitis B or C infection with a Prevalence of 2. 8% (95% confidence interval: 1. 4% to 5. 1%). Multivariable analyses showed that association between the need for hemodialysis (OR=13. 52; p=0. 083) and severity of chronic kidney disease (OR=0. 28; p=0. 072) with incidence of hepatitis infection was borderline. However, risk of Hepatitis B or C infection was 5. 9-fold greater in girls compared to boys (OR=5. 94; p=0. 047). Conclusion: The present study showed that the Prevalence of Hepatitis B and C were 2. 5% and 1. 4%, in Children with chronic kidney disease, respectively. The Prevalence of mentioned infections was significantly higher in girls compared to boys.

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APA: Copy

ATAEI, NEAMATOLLAH, HOSSEINI, MOSTAFA, YOUSEFIFARD, MAHMOUD, ORAII, ALIREZA, ATAEI, FATEMEH, ABBASI, ARASH, RAEESSI, NEDA, & MOGHTADERI, MASTANEH. (2018). Seroprevalence of Hepatitis B and C Virus Infection in Children with Chronic Kidney Diseases; A Historical Cohort Study. INTERNATIONAL JOURNAL OF PEDIATRICS, 6(1 (49)), 6911-6917. SID. https://sid.ir/paper/337712/en

Vancouver: Copy

ATAEI NEAMATOLLAH, HOSSEINI MOSTAFA, YOUSEFIFARD MAHMOUD, ORAII ALIREZA, ATAEI FATEMEH, ABBASI ARASH, RAEESSI NEDA, MOGHTADERI MASTANEH. Seroprevalence of Hepatitis B and C Virus Infection in Children with Chronic Kidney Diseases; A Historical Cohort Study. INTERNATIONAL JOURNAL OF PEDIATRICS[Internet]. 2018;6(1 (49)):6911-6917. Available from: https://sid.ir/paper/337712/en

IEEE: Copy

NEAMATOLLAH ATAEI, MOSTAFA HOSSEINI, MAHMOUD YOUSEFIFARD, ALIREZA ORAII, FATEMEH ATAEI, ARASH ABBASI, NEDA RAEESSI, and MASTANEH MOGHTADERI, “Seroprevalence of Hepatitis B and C Virus Infection in Children with Chronic Kidney Diseases; A Historical Cohort Study,” INTERNATIONAL JOURNAL OF PEDIATRICS, vol. 6, no. 1 (49), pp. 6911–6917, 2018, [Online]. Available: https://sid.ir/paper/337712/en

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